Effect of leaf essential oil from Piper solmsianum C.DC. in mice behaviour
An. acad. bras. ciênc
; 73(1): 33-7, Mar. 2001. ilus, tab
Article
in English
| LILACS
| ID: lil-281082
Responsible library:
BR1.1
RESUMO
The essential oil from Piper solmsianum leaves and its major compound (sarisan) were tested to verify their influences upon mice behaviour. The essential oil was obtained by hydrodistillation in a modified Clevenger extractor and analysed by GC/ MS. This analysis revealed in the oil the presence of monoterpenes, sesquiterpenes and of arylpropanoids. The compound sarisan, a myristicin analogue, was isolated from the oil to perform the pharmacological tests. Emulsions of the oil and of sarisan (5.0 and 10.0 percent v/v) were used in the tests. Pentobarbital (30 mg/ kg s.c.) or diazepam (2.5 mg/ kg s.c.) were tested as standard drugs to verify depressant or anxiolytic effects, respectively. Both essential oil and sarisan showed to have exciting and depressant effects in the tested animals
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Behavior, Animal
/
Plant Oils
/
Oils, Volatile
Limits:
Animals
Language:
English
Journal:
An. acad. bras. ciênc
Journal subject:
Science
Year:
2001
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Jardim Botânico do Rio de Janeiro/BR
/
Universidade Federal do Rio de Janeiro/BR