Biventricular pacing improves clinical behavior and reduces prevalence of ventricular arrhythmia in patients with heart failure
Arq. bras. cardiol
; 78(1): 110-113, Jan. 2002. tab
Article
in English
| LILACS
| ID: lil-301423
Responsible library:
BR1.1
ABSTRACT
PURPOSE:
To analyze the influence of biventricular pacing (BP) on clinical behavior, ventricular arrhythmia (VA) prevalence, and left ventricular ejection fraction (LV EF) by gated ventriculography.METHODS:
Twenty-four patients with left bundle branch block (LBBB) and NYHA class III and IV underwent pacemaker implantation and were randomized either to the conventional or BP group, all receiving BP after 6 months.RESULTS:
Sixteen patients were in NYHA class IV (66.6 per cent) and 8 were in class III (33.4 per cent). After 1-year follow-up, 14 patients were in class II (70 per cent) and 5 were in class III (25 per cent). Two sudden cardiac deaths occurred. A significant reduction in QRS length was found with BP (p=0.006). A significant statistical increase, from a mean of 19.13 ñ 5.19 per cent (at baseline) to 25.33 ñ 5.90 per cent (with BP) was observed in LVEF Premature ventricular contraction prevalence decreased from a mean of 10,670.00 ñ 12,595.39 SD or to a mean of 3,007.00 ñ 3,216.63 SD PVC/24 h with BP (p<0.05). Regarding the hospital admission rate over 1 year, we observed a significant reduction from 60. To 16 admissions with BP (p<0.05).CONCLUSION:
Patients with LBBB and severe heart failure experienced, with BP, a significant NYHA class and LVEF improvement. A reduction in the hospital admission rate and VA prevalence also occurred.
Full text:
Available
Collection:
International databases
Health context:
SDG3 - Health and Well-Being
/
SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases
Health problem:
Target 3.4: Reduce premature mortality due to noncommunicable diseases
/
Cardiovascular Disease
/
Other circulatory Diseases
Database:
LILACS
Main subject:
Bundle-Branch Block
/
Cardiac Output, Low
/
Cardiac Pacing, Artificial
Type of study:
Controlled clinical trial
/
Observational study
/
Prevalence study
/
Risk factors
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
Arq. bras. cardiol
Journal subject:
Cardiology
Year:
2002
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
University of Säo Paulo/BR