Epidemia de febre clássica de dengue causada pelo sorotipo 2 em Araguaina, Tocantins, Brasil / Outbreak of classical fever of dengue caused by serotype 2 in Araguaiana, Tocantins, Brazil
Rev. Inst. Med. Trop. Säo Paulo
; 35(2): 141-148, Mar.-Apr. 1993.
Article
in Pt
| LILACS
| ID: lil-320576
Responsible library:
BR1.1
ABSTRACT
We report the first outbreak of dengue fever caused by dengue 2 (DEN 2) in Araguaina, Tocantins State. Four hundred people of 74 families, living at S. João, Araguaina Sul and Neblina districts were questioned and then bled, in order to obtain sera to test for anti-dengue antibodies. If a person was sick, a small quantity of blood was collected for virus isolation. The main clinical picture of disease was characterized by fever, headache, myalgias, arthralgias and skin rash. Were obtained 1,105 (56 females and 45 males of Culex quinquefasciatus and 567 females and 437 males of Aedes aegypti) mosquitoes from larvae collected in Araguaina. The females of Aedes aegypti obtained from larvae were allowed to feed on 8 febrile patients. The diagnosis of infection was made by both virus isolation into Aedes albopictus (C6/36) cells, and serology, by Hemagglutination-inhibition (HI) and IgM capture ELISA (MAC ELISA). No virus was isolated from mosquitoes. Although five strains of DEN 2 were obtained from humans, and another 111 infections were diagnosed serologically (IgM positive). The positivity rate of the samples was 27.75 (111 of 400), while that of the families was 66.2 (45 of 72), where at least one member of the each family was infected. It was also detected 26.1 of asymptomatic infections. All age groups were affected. Therefore, the infection was more frequent in females (33.5) than males (23.8).(ABSTRACT TRUNCATED AT 250 WORDS)
Full text:
1
Collection:
01-internacional
Database:
LILACS
Main subject:
Dengue
Type of study:
Screening_studies
Limits:
Adolescent
/
Adult
/
Child
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Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Newborn
Country/Region as subject:
America do sul
/
Brasil
Language:
Pt
Journal:
Rev. Inst. Med. Trop. Säo Paulo
Journal subject:
MEDICINA TROPICAL
Year:
1993
Document type:
Article
Affiliation country:
Brazil
Country of publication:
Brazil