New prevalence estimate of TT virus (TTV) infection in low- and high-risk population from Säo Paulo, Brazil
Rev. Inst. Med. Trop. Säo Paulo
; 44(4): 233-234, July-Aug. 2002. tab
Article
in English
| LILACS, Sec. Est. Saúde SP
| ID: lil-321227
Responsible library:
BR1.1
ABSTRACT
The prevalence of TT virus (TTV) infection was investigated by Polymerase Chain Reaction (PCR) in low- (blood donors and healthy children/adolescents) and high-risk (hemophiliacs) groups from Säo Paulo, Brazil. Primers based on the untranslated region (UTR) of the viral genome proved to be much more ubiquitous, leading to much higher frequencies for both groups ( > or = 81 percent) than the earlier N22-PCR directed to the open reading frame 1 (blood donors, 5.5 percent, and hemophiliacs, 42.3 percent). The UTR-PCR also revealed an interesting profile for healthy children/adolescents very high prevalence at the early years and significant decrease in male teenagers. The N22-PCR, in turn, demonstrated higher frequency in hemophiliacs treated with fresh blood products (58 percent), than in those treated with virus-inactivated clotting factors (9.4 percent) and blood donors (5.5 percent)
Full text:
Available
Collection:
National databases
/
Brazil
Database:
LILACS
/
Sec. Est. Saúde SP
Main subject:
Torque teno virus
/
DNA Virus Infections
Type of study:
Etiology study
/
Prevalence study
/
Risk factors
Limits:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Rev. Inst. Med. Trop. Säo Paulo
Year:
2002
Document type:
Article
Institution/Affiliation country:
Fundaçäo Pró-Sangue Hemocentro de São Paulo/BR
/
Fundaçäo Pró-Sangue Hemocentro de Säo Paulo/BR
/
Institute of Infectology "Emílio Ribas"/BR
/
University of Säo Paulo/BR