Repercussões hemodinâmicas e metabólicas da infusäo de soro fisiológico para manutençäo da volemia na oclusäo temporária da aorta abdominal / Metabolic and hemodynamic effects of saline infusion to maintain volemia on temporary abdominal aortic occlusion
Arq. bras. cardiol
; Arq. bras. cardiol;79(4): 395-404, Oct. 2002. tab
Article
in Pt, En
| LILACS
| ID: lil-323360
Responsible library:
BR1.1
RESUMO
OBJECTIVE:
To analyze hemodynamic and metabolic effects of saline solution infusion in the maintenance of blood volume in ischemia-reperfusion syndrome during temporary abdominal aortic occlusion in dogs.METHODS:
We studied 20 dogs divided into 2 groups the ischemia-reperfusion group (IRG, n=10) and the ischemia-reperfusion group with saline solution infusion aiming at maintaining mean pulmonary arterial wedge pressure between 10 and 20 mmHg (IRG-SS, n=10). All animals were anesthetized with sodium thiopental and maintained on spontaneous ventilation. Occlusion of the supraceliac aorta was obtained with inflation of a Fogarty catheter inserted through the femoral artery. After 60 minutes of ischemia, the balloon was deflated, and the animals were observed for another 60 minutes of reperfusion.RESULTS:
IRG-SS dogs did not have hemodynamic instability after aortic unclamping, and the mean systemic blood pressure and heart rate were maintained. However, acidosis worsened, which was documented by a greater reduction of arterial pH that occurred especially due to the absence of a respiratory response to metabolic acidosis that was greater with the adoption of this procedure.CONCLUSION:
Saline solution infusion to maintain blood volume avoided hemodynamic instability after aortic unclamping. This procedure, however, caused worsening in metabolic acidosis in this experimental model
Full text:
1
Collection:
01-internacional
Database:
LILACS
Main subject:
Blood Volume
/
Sodium Chloride
/
Reperfusion Injury
/
Hemodynamics
Limits:
Animals
Language:
En
/
Pt
Journal:
Arq Bras Cardiol
/
Arq. bras. cardiol
/
Arq. bras. cardiol. (Online)
/
Arquivos brasileiros de cardiologia (Impresso)
Journal subject:
CARDIOLOGIA
Year:
2002
Document type:
Article
Affiliation country:
Brazil
Country of publication:
Brazil