Lipid and acute-phase protein alterations in HIV-1 infected patients in the early stages of infection: correlation with CD4+ lymphocytes
Braz. j. infect. dis
; 5(4): 192-199, Aug. 2001. tab
Article
in English
| LILACS
| ID: lil-339409
Responsible library:
BR11.1
RESUMO
Lipid and acute-phase protein alterations have been described in various infection diseases, and they have been recorded during the early stages of HIV infection. Lipid and acute-phase protein profiles also have been correlated with cellular immunological abnormalities. To document these correlations during HIV infection, we studied 75 HIV-infected patients and 26 HIV-negative controls. Patients were classified according to the criteria proposed by the Walter Reed army Institute as WR-1 (CD4lymphocytes, 1154+268/mm3), WR-2 (CD4,793+348/mm3) and WR3/4(CD4287+75mm3). Triglycerides, total cholesterol and HDL-cholesterol concentrations were measurede by enzymatic methods. Immunoglobulins (IgA and IgG) and acute-phase proteins (haptoglobin, &,-acid glycoprotein, C-reactive protein and transferrin) were determined by immunonephelometry. Haptoglobin levels were significantly increased in HIV-positive patients and correlated with the progression of HIV-infection (control
Full text:
Available
Collection:
International databases
Health context:
SDG3 - Health and Well-Being
Health problem:
Target 3.3: End transmission of communicable diseases
Database:
LILACS
Main subject:
Acute-Phase Proteins
/
HIV Infections
/
HIV Seropositivity
/
HIV Seronegativity
/
Lipids
Limits:
Humans
Language:
English
Journal:
Braz. j. infect. dis
Journal subject:
Communicable Diseases
Year:
2001
Document type:
Article
Full text:
Available
Collection:
International databases
Health context:
SDG3 - Health and Well-Being
Health problem:
Target 3.3: End transmission of communicable diseases
Database:
LILACS
Main subject:
Acute-Phase Proteins
/
HIV Infections
/
HIV Seropositivity
/
HIV Seronegativity
/
Lipids
Limits:
Humans
Language:
English
Journal:
Braz. j. infect. dis
Journal subject:
Communicable Diseases
Year:
2001
Document type:
Article