The 245 kb amplified chromosome of Leishmania (V. ) braziliensis contains a biopterin transporter gene
Mem. Inst. Oswaldo Cruz
; 98(3): 377-378, Apr. 2003. ilus
Article
in English
| LILACS
| ID: lil-340117
Responsible library:
BR1.1
ABSTRACT
Leishmania (V.) braziliensis M2903 presents a small linear and stable 245 kb chromosome originating from a genomic amplification. Similar amplifications present in other species of Leishmania contain a gene coding for a biopterin transporter. Since Leishmania is auxotrophic for this metabolite, this amplification could result from the need to better capture biotpterin from growth media under specific circumstances. In this paper we show that this gene is also present in L. (V.) braziliensis small chromosome, which shares sequences with other genomic amplifications already described
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Biopterins
/
Leishmania braziliensis
Limits:
Animals
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2003
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Fiocruz/BR
/
Universidade do Estado do Rio de Janeiro/BR