Integrones y cassettes genéticos de resistencia: estructura y rol frente a los antibacterianos / Integrons and resistance gene cassettes: structure and role against antimicrobials
Rev. méd. Chile
; 132(5): 619-626, mayo 2004. ilus
Article
in Es
| LILACS
| ID: lil-384422
Responsible library:
CL12.1
ABSTRACT
Bacteria have developed sophisticated and successful genetic mechanisms to evade the action of antimicrobials. Bacterial multiresistance has caused serious problems in the treatment of nosocomial infections. Integrons and gene cassettes are considered the main genetic elements in the evolution of plasmids and transposons that actively participate in the mobilization of genes, codifying different bacterial resistance mechanisms. This article reviews the historical and structural aspects of integrons and resistance gene cassettes and the presence of these structures in Gram negative bacteria isolated from Chilean hospitals in the last ten years (Rev MÚd Chile 2004; 132 619-26).
Full text:
1
Collection:
01-internacional
Database:
LILACS
Main subject:
Microbial Sensitivity Tests
/
Drug Resistance, Bacterial
/
Integrons
Language:
Es
Journal:
Rev. méd. Chile
Journal subject:
MEDICINA
Year:
2004
Document type:
Article
/
Project document
Affiliation country:
Chile
Country of publication:
Chile