Determinación de factores trombofílicos en pacientes con trombosis venosas retinianas / Markers of thrombophilia in patients with retinal vein thrombosis
Rev. méd. Chile
; 133(2): 167-174, feb. 2005. ilus, tab
Article
in Es
| LILACS
| ID: lil-398048
Responsible library:
CL12.1
ABSTRACT
Background:
Thrombophilia is an alteration of hemostasis that increases the risk to venous or arterial thrombosis. This condition may be the underlying cause of retinal vein thrombosis.Aim:
To study the presence of thrombophilia in patients with retinal vein thrombosis. Patients andmethods:
Prospective study of 55 patients aged 22 to 86 years, with retinal vein thrombosis (central or branch). Antithrombin III, coagulant protein C, functional protein S, resistance to activated C protein, homocysteine, prothrombin G20210A gene, lupus anticoagulant and anticardiolipin antibodies were measured in all.Results:
Seventeen patients had thrombophilic markers (antiphospholipid syndrome in seven, hyperhomocysteinemia in six and resistance to protein C in three). Of these 17 patients, 53percent had high blood pressure, 35percent an abnormal serum lipid profile and 23percent a personal history of thrombosis. The thrombosis was central in 12 (ischemic in four) and of a branch in five (ischemic in two).Conclusions:
Thrombophilic markers must be assessed in patients with retinal vein thrombosis.
Full text:
1
Collection:
01-internacional
Database:
LILACS
Main subject:
Retinal Vein Occlusion
/
Thrombophilia
Type of study:
Clinical_trials
/
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
Es
Journal:
Rev. méd. Chile
Journal subject:
MEDICINA
Year:
2005
Document type:
Article
Affiliation country:
Chile
Country of publication:
Chile