Central nervous system paracoccidioidomycosis: case report and review
Invest. clín
; 45(3): 277-288, sept. 2004. ilus, tab
Article
in English
| LILACS
| ID: lil-402023
Responsible library:
VE1.1
ABSTRACT
Paracoccidioidomycosis is a systemic infection caused by a dimorphic fungus (Paracoccidioides brasiliensis). The most common lesions frequently occur in the bucopharinx mucosa. Other lesions occur in the adrenal glands, liver, bone, gastrointestinal tract, lungs and nervous system. We report here a case of neuroparacoccidioidomycosis. The patient was a 49 year-old male, who consulted due to neurological symptoms (cephalalgia, speech difficulty and one tonic clonic seizure with urinary incontinence) of eight months duration. Upon physical examination it was observed an emaciated male with nail clubbing, a skin ulcer with raised edges and a crusted bottom of 4 × 2 cm in diameter located in the right supraclavicular region and an ulcerated lesion in the left tonsil with edema. The rest of the physical examination reveled a discrete left side hemiparesis and pulmonary rales in the left hemitorax. The fungus was identified through direct examination of cerebrospinal fluid (CSF). The histopathology of suprarenal, lungs, brain and skin showed multiple paracoccidioidal granulomas. To the best of our knowledge, this is the third case reported in the literature. We review the literature on the pathogenesis and prevalence of neuroparacoccidioidomycosis
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Paracoccidioidomycosis
/
Central Nervous System
Type of study:
Prognostic study
/
Risk factors
Limits:
Adult
/
Humans
/
Male
Country/Region as subject:
South America
/
Venezuela
Language:
English
Journal:
Invest. clín
Journal subject:
Biologia
/
Medicine
/
Relatos de Casos
Year:
2004
Document type:
Article
Affiliation country:
Venezuela