Mast cell changes in experimental diabetes: focus on attenuation of allergic events
Mem. Inst. Oswaldo Cruz
; 100(supl.1): 121-125, Mar. 2005.
Article
in English
| LILACS
| ID: lil-402187
Responsible library:
BR1.1
ABSTRACT
The prevalence of atopic diseases and diabetes is increasing worldwide though the concurrence of these pathologies in individual patients is found less frequent than it would be predicted. Moreover, co-existence of diabetes and allergy is generally marked by attenuation of their respective symptoms, and effective treatment of one disease exacerbates the other. This review gives an update of the state-of-the-art concerning the intercurrence of allergy and diabetes, particularly focusing on the consequences to the allergen-evoked vascular and cellular changes. It is proposed that the reduction in mast cell numbers and reactivity may be a pivotal mechanism behind the mutual exclusion phenomenon.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Diabetes Mellitus, Experimental
/
Hypersensitivity
/
Mast Cells
Type of study:
Etiology study
/
Risk factors
Limits:
Animals
/
Humans
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2005
Document type:
Article
Affiliation country:
Brazil
/
France
Institution/Affiliation country:
Instituto Oswaldo Cruz/BR
/
Université de Rennes/FR