Seroprevalence of hepatitis B and C virus markers among blood donors in Rio de Janeiro, Brazil, 1998-2005
Mem. Inst. Oswaldo Cruz
; 101(6): 673-676, Sept. 2006. graf, tab
Article
in English
| LILACS
| ID: lil-437063
Responsible library:
BR1.1
ABSTRACT
The prevalence of infection by hepatitis B (HBV) and C (HCV) viruses varies among geographical regions. In order to determine the prevalence of HBV and HCV infection in voluntary blood donors we evaluated the prevalence of HBsAg, anti-HBc, and anti-HCV markers of 128,497 blood donor samples collected from 1998 to 2005 in the state of Rio de Janeiro. These markers were analyzed by immunoenzymatic tests, as determined by the Ministry of Health. Data were obtained from the Sorology Laboratory of the Hemoterapy Service of the Instituto Nacional de Câncer, Rio de Janeiro. Overall prevalence estimates were 0.27 percent for HBsAg, 3.68 percent for anti-HBc, and 0.90 percent for anti-HCV. There was a significant decrease in the overall prevalence of HBsAg (from 0.36 to 0.14 percent) and anti-HBc (from 6.12 to 2.05 percent) in the period encompassed between 1998-2005. Similarly, there was a decline in anti-HCV prevalence rates in Brazilian blood donors, from 1.04 percent in 1998 to 0.79 percent in 2004, with an increase of HCV prevalence to 1.09 percent in 2005. These prevalence estimates were higher than those found in other countries, indicating high rates of infection by HBV and HCV and a persistent risk of HBV and HCV transmission by transfusion.
Full text:
Available
Collection:
International databases
Health context:
SDG3 - Health and Well-Being
Health problem:
Target 3.3: End transmission of communicable diseases
Database:
LILACS
Main subject:
Blood Donors
/
Hepatitis C
/
Hepatitis C Antibodies
/
Hepatitis B
/
Hepatitis B Core Antigens
/
Hepatitis B Surface Antigens
Type of study:
Observational study
/
Prevalence study
/
Risk factors
Limits:
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2006
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Fiocruz/BR
/
Fundação Oswaldo Cruz/BR
/
Instituto Nacional de Câncer/BR
/
Instituto Nacional do Câncer/BR