Molecular approaches for the detection of Schistosoma mansoni: possible applications in the detection of snail infection, monitoring of transmission sites, and diagnosis of human infection
Mem. Inst. Oswaldo Cruz
; 101(supl.1): 145-148, Oct. 2006.
Article
in English
| LILACS
| ID: lil-441239
Responsible library:
BR1.1
ABSTRACT
The detection of specific DNA sequences by polymerase chain reaction (PCR) has proved extremely valuable for the analysis of genetic disorders and the diagnosis of a variety of infectious disease pathogens. However, the application to the detection of Schistosoma mansoni is rare, despite a recommendation of the World Health Organization that a major focus of research on schistosomiasis should be on the development and evaluation of new strategies and tools for control of the disease. In this context, a few studies were published for the detection of the parasite in snails, monitoring of cercariae in water bodies, and diagnosis of human infection. The present minireview describes sensitive and specific PCR based systems to detect S. mansoni, indicating possible applications in the detection of snail infection, monitoring of transmission sites, and diagnosis of human infection.
Full text:
Available
Collection:
International databases
Health context:
SDG3 - Health and Well-Being
/
Neglected Diseases
Health problem:
Target 3.8 Achieve universal access to health
/
Target 3.3: End transmission of communicable diseases
/
Helminthiasis
/
Neglected Diseases
/
Schistosomiasis
/
Zoonoses
Database:
LILACS
Main subject:
Schistosoma mansoni
/
Schistosomiasis
/
Biomphalaria
/
Polymerase Chain Reaction
/
Fresh Water
Type of study:
Diagnostic study
/
Practice guideline
Limits:
Animals
/
Humans
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2006
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Fiocruz/BR