Anti-inflammatory activity of the apolar extract from the seaweed Galaxaura marginata (Rhodophyta, Nemaliales)
J. venom. anim. toxins incl. trop. dis
; 13(2): 544-548, 2007. graf
Article
in English
| LILACS
| ID: lil-452846
Responsible library:
BR33.1
ABSTRACT
The red seaweed Galaxaura marginata (Ellis & Solander) Lamouroux, well known by the antibacterial activity of its polar extract and the cytotoxic activity of its oxygenated desmosterol, showed anti-inflammatory action in its apolar fraction. Topical anti-inflammatory activity was observed in samples collected at São Sebastião channel, northern littoral of São Paulo State, Brazil. The apolar extract and its fractions obtained through Thin-Layer Chromatography (TLC) reduced the topical inflammation produced by croton oil in mouse ear. Such data indicated that the apolar extract from the marine red alga G. marginata displayed anti-inflammatory activity (since 1mg/ear extract reduced 95±0.5 percent inflammation), which could be the result of the synergic activity of the four fractions present in the apolar extract.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Seaweed
/
Croton Oil
/
Rhodophyta
/
Anti-Inflammatory Agents
Language:
English
Journal:
J. venom. anim. toxins incl. trop. dis
Journal subject:
Toxicology
Year:
2007
Document type:
Article
/
Project document
Affiliation country:
Brazil
Institution/Affiliation country:
University of São Paulo/BR