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Paracoccidioidomycosis: no genetic damage in human peripheral blood cells of patients assessed by single-cell gel (comet) assay
Ribeiro-Vieira, Renata Aparecida Martinez Antunes; Ribeiro, Daniel Araki; Salvadori, Daisy Maria Favero; Marques, Sílvio Alencar.
Affiliation
  • Ribeiro-Vieira, Renata Aparecida Martinez Antunes; São Paulo State University. Botucatu School of Medicine. Department of Dermatology and Radiotherapy. Botucatu. BR
  • Ribeiro, Daniel Araki; São Paulo Federal University. Department of Health Sciences. Santos. BR
  • Salvadori, Daisy Maria Favero; São Paulo State University. Botucatu School of Medicine. Department of Pathology. Botucatu. BR
  • Marques, Sílvio Alencar; São Paulo State University. Botucatu School of Medicine. Department of Dermatology and Radiotherapy. Botucatu. BR
Rev. Soc. Bras. Med. Trop ; 40(4): 476-478, jul.-ago. 2007.
Article in English | LILACS | ID: lil-460259
Responsible library: BR1.1
ABSTRACT
Paracoccidioidomycosis is a systemic fungal infection caused by Paracoccidioides brasiliensis. As infectious diseases can cause DNA damage, the authors aimed at analyzing DNA breakage in peripheral blood cells of patients with paracoccidioidomycosis by using the comet assay. The results suggested that paracoccidioidomycosis does not cause genotoxicity.
RESUMO
Paracoccidioidomicose é micose sistêmica causada pelo Paracoccidioides brasiliensis. Considerando que doenças infecciosas são capazes de induzir danos genéticos, o objetivou-se analisar quebras no DNA em células de sangue periférico de pacientes com paracoccidioidomicose utilizando o teste do cometa. Os resultados sugeriram que essa enfermidade não exerce genotoxicidade.
Subject(s)

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Full text: Available Collection: International databases Database: LILACS Main subject: Paracoccidioidomycosis / DNA Damage / Leukocytes, Mononuclear Limits: Adult / Humans Language: English Journal: Rev. Soc. Bras. Med. Trop Journal subject: Tropical Medicine Year: 2007 Document type: Article Affiliation country: Brazil Institution/Affiliation country: São Paulo Federal University/BR / São Paulo State University/BR
Fulltext
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Full text: Available Collection: International databases Database: LILACS Main subject: Paracoccidioidomycosis / DNA Damage / Leukocytes, Mononuclear Limits: Adult / Humans Language: English Journal: Rev. Soc. Bras. Med. Trop Journal subject: Tropical Medicine Year: 2007 Document type: Article Affiliation country: Brazil Institution/Affiliation country: São Paulo Federal University/BR / São Paulo State University/BR