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Síndrome cerebeloso secundario a granulomas de fosa posterior y tuberculosis multisistémica en un paciente con SIDA / Cerebelous syndrome by infratentorial brain tuberculornas and mutisystemic tuberculosis in AIDS patient
Navarrete A., Claudio; Rosas K., Mónica; Sáez M., David; Tenhamm F., Eugenio; Nogales-Gaete, Jorge.
Affiliation
  • Navarrete A., Claudio; Hospital Clínico Regional de Valdivia. Servicio de Neurología y Neurocirugía. Valdivia. CL
  • Rosas K., Mónica; Hospital de Puerto Montt. Servicio de Neurología y Neurocirugía. CL
  • Sáez M., David; Universidad de Chile. Departamento de Neurología. Campus Sur. Santiago. CL
  • Tenhamm F., Eugenio; Hospital Barros Luco Trudeau. Servicio de Neurología. Santiago. CL
  • Nogales-Gaete, Jorge; Hospital Barros Luco Trudeau. Servicio de Neurología. Santiago. CL
Rev. chil. infectol ; 25(2): 122-126, abr. 2008. ilus, tab
Article in Spanish | LILACS | ID: lil-483190
Responsible library: BR1.1
RESUMEN
Presentamos el caso clínico de un paciente que consultó por un síndrome cerebeloso y diplopía, asociados a pérdida de peso de 10 kilos en 6 meses y adenopatías múltiples. El estudio imagenológico cerebral demostró la presencia de lesiones de aspecto granulomatoso a nivel cerebeloso y mesencefálico, sin alteración citoquímica del líquido cefalorraquídeo. Las baciloscopias de orina y de la biopsia ganglionar fueron positivas y permitieron el diagnóstico de tuberculosis (TBC) sistémica. La serología para VIH resultó positiva en sangre con un recuento de linfocitos CD4 de 590 cel/mm3, clasificándose el caso como SIDA etapa Cl. El paciente fue tratado con el esquema antituberculoso según norma nacional, con buena respuesta clínica e imagenológica. La presentación de tuberculomas infratentoriales sin meningitis, como primera causa de pesquisa de TBC y SIDA no es habitual, de allí nuestro interés por comunicar el caso.
ABSTRACT
We present a clinical case of a patient who consulted for a cerebelous syndrome and diplopia associated to 10 kg weight loss in six months and multiple adenopathies. Cerebral imagenology study evidenced the presence of granulamatous masses at the cerebellum and midbrain level, there were no cerebrospinal fluid abnormalities. Systemic tuberculosis (TB) diagnosis was done based in finding of acid-fast bacilli positive staining in urine and lymph node biopsy. HIV infection was documented by ELISA serology. CD4 cell count was 590 cell/mm3, classifying the case a AIDS Cl stage. TB was treated according to national guidelines leading to good clinical and imagenology evolution. The clinical case scenario of infratentorial tuberculomas without meningitis as a first manifestation of TB and AIDS is unusual, generating our interest in reporting this case.
Subject(s)

Full text: Available Collection: International databases Health context: Neglected Diseases Health problem: Neglected Diseases / Tuberculosis / Zoonoses Database: LILACS Main subject: Cerebellar Diseases / Tuberculoma, Intracranial / AIDS-Related Opportunistic Infections / Antitubercular Agents Type of study: Diagnostic study / Practice guideline Limits: Adult / Humans / Male Language: Spanish Journal: Rev. chil. infectol Journal subject: Communicable Diseases Year: 2008 Document type: Article Affiliation country: Chile Institution/Affiliation country: Hospital Barros Luco Trudeau/CL / Hospital Clínico Regional de Valdivia/CL / Hospital de Puerto Montt/CL / Universidad de Chile/CL
Full text: Available Collection: International databases Health context: Neglected Diseases Health problem: Neglected Diseases / Tuberculosis / Zoonoses Database: LILACS Main subject: Cerebellar Diseases / Tuberculoma, Intracranial / AIDS-Related Opportunistic Infections / Antitubercular Agents Type of study: Diagnostic study / Practice guideline Limits: Adult / Humans / Male Language: Spanish Journal: Rev. chil. infectol Journal subject: Communicable Diseases Year: 2008 Document type: Article Affiliation country: Chile Institution/Affiliation country: Hospital Barros Luco Trudeau/CL / Hospital Clínico Regional de Valdivia/CL / Hospital de Puerto Montt/CL / Universidad de Chile/CL
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