Experimental infection parameters in Galea spixii (Rodentia: Caviidae) with Leishmania infantum chagasi
Mem. Inst. Oswaldo Cruz
; 103(6): 545-548, Sept. 2008. ilus, tab
Article
in English
| LILACS
| ID: lil-495729
Responsible library:
BR1.1
ABSTRACT
In order to better understand the epidemiological transmission network of leishmaniasis, an endemic disease in Northeast Brazil, we investigated the susceptibility of Spix yellow-toothed cavies (Galea spixii) to the Leishmania infantum chagasi parasite. Nine cavies were experimentally infected, separated into three groups and monitored at 30, 90 and 180 days, respectively. Amastigotes were identified in the spleen slides of two cavies killed 180 days after infection. Antibodies against the L. i. chagasi were identified in one of the cavies. This demonstrates that G. spixii is in fact capable of maintaining a stable infection by L. i. chagasi without alterations in biochemical and hematological parameters of the host and without perceivable micro and macroscopic lesions.
Full text:
Available
Collection:
International databases
Health context:
Neglected Diseases
Health problem:
Zoonoses
Database:
LILACS
Main subject:
Antibodies, Protozoan
/
Leishmania infantum
/
Leishmaniasis, Visceral
Type of study:
Prognostic study
Limits:
Animals
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2008
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Estadual do Rio Grande do Norte/BR
/
Universidade Federal do Rio Grande do Norte/BR