Alterações esofágicas em modelo de esclerodermia induzido por colágeno V em coelhos / Manifestations in the esophagus in the sclerodermia model induced by type V collagen in rabbits
Rev. med. (Säo Paulo)
; 86(3): 163-173, jul.-set. 2007. ilus, tab
Article
in Portuguese
| LILACS
| ID: lil-497270
Responsible library:
BR66.1
RESUMO
Introdução:
a esclerose sistêmica progressiva acomete diversas vísceras, das quais o esôfago é uma das frequentemente lesadas. No entanto, o mecanismo de autoimunidade nesta enfermidade é ainda desconhecida...ABSTRACT
Backgrounds Sclerosis systemic that usually affects the esophagus. However its patologic mechanism is still unknown. Objective:
Evaluate the manifestation of the esophagus in a experimental model of scleroderma induced by type V collagen in rabbits. Matherial andMethods:
39 rabbits submited to the model immunization were morfologicaly analised.Results:
A progressive deposit of collagen fibers was observed in H&E and Tricomico of Masson. Which was confirmed by the imunofluorescence.Conclusion:
We concluded that the characteristics observeds are similar to what happens in the esophagus of human, but in an earlier period...
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Scleroderma, Localized
/
Collagen Type V
/
Esophageal Diseases
Type of study:
Prognostic study
Limits:
Animals
Language:
Portuguese
Journal:
Rev. med. (Säo Paulo)
Year:
2007
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade de São Paulo/BR
