Prevalencia de anticuerpos anti-VHC y del antígeno de superficie de la hepatitis B en pacientes tratados con hemodiálisis / Prevalence of anti-HCV antibodies and of the hepatitis B surface antigen in patients treated with hemodialysis
Rev. cuba. med
; 47(1)ene.-mar. 2008. ilus
Article
in Spanish
| LILACS
| ID: lil-499488
Responsible library:
CU1.1
RESUMEN
Se estudiaron 108 pacientes con tratamiento de hemodiálisis para determinar la prevalencia de anticuerpos contra el virus de la hepatitis C (anti-VHC) y del antígeno de superficie de la hepatitis B (HBsAg) empleando la tecnología SUMA. Se obtuvo elevada prevalencia de anticuerpos contra el virus de la hepatitis C (90 por ciento) y menor prevalencia del HBsAg (4 por ciento). Se hallaron títulos protectores de anticuerpos anti-HBsAg en el 91 por ciento de los pacientes. Se observó que los pacientes con niveles de anticuerpos de 10 UI/L resultaron protegidos lo que se corresponde con una respuesta efectiva a nuestro esquema de vacunación y con mejores resultados que lo normalmente reportado para este tipo de paciente (100 UI/L). Se presentaron valores persistentemente normales de actividad enzimática de la enzima glutámico-pirúvica (TGP) en el 65 por ciento de los pacientes, lo que podría indicar una enfermedad crónica y corrobora la frecuente disminución que se observa en la actividad enzimática de la TGP.
ABSTRACT
108 hemodialysis patients were studied to determine the prevalence of antibodies against hepatitis C virus (anti-HCV) and of the hepatitis B surface antigen (HBsAg) by using the SUMA technology. It was obtained an elevated prevalence of antibodies against the hepatitis C virus (90 percent) and a lower prevalence of of HBsAg (4 percent). Titres protecting anti-HBsAg antibodies were found in 91 percent of the patients. It was observed that the patients with antibody levels of 10 UI/L were protected, which corresponds to an effective response to our vaccination scheme and to better results than the ones normally reported for this type of patient (100 UI/L). Persistently normal values of the enzymatic activity of the glutamic piruvic enzyme (GPT) were present in 65 percent of the patients, which could indicate a chronic disease and corroborate the frequent decrease observed in the enzymatic activity of GPT.
Full text:
Available
Collection:
International databases
Health context:
SDG3 - Health and Well-Being
Health problem:
Target 3.3: End transmission of communicable diseases
Database:
LILACS
Main subject:
Renal Dialysis
/
Hepatitis C Antibodies
/
Hepatitis B Antibodies
Type of study:
Prevalence study
/
Risk factors
/
Screening study
Limits:
Humans
Language:
Spanish
Journal:
Rev. cuba. med
Journal subject:
Medicine
Year:
2008
Document type:
Article
Affiliation country:
Cuba
Institution/Affiliation country:
Hospital Clinicoquirúrgico Hermanos Ameijeiras/CU
/
Instituto de Nefrología Abelardo Buch/CU