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Extensively drug-resistant tuberculosis: a case report and literature review
Araújo-Filho, João Alves de; Vasconcelos-Jr, Arioldo Carvalho; Sousa, Eduardo Martins de; Silveira, Colombina da; Ribeiro, Elisangela; Kipnis, André; Junqueira-Kipnis, Ana Paula.
Affiliation
  • Araújo-Filho, João Alves de; Federal University of Goiás. Institute of Tropical Pathology and Public Health.
  • Vasconcelos-Jr, Arioldo Carvalho; Federal University of Goiás. Institute of Tropical Pathology and Public Health.
  • Sousa, Eduardo Martins de; Federal University of Goiás. Institute of Tropical Pathology and Public Health.
  • Silveira, Colombina da; Tropical Diseases Hospital Dr. Anuar Auad.
  • Ribeiro, Elisangela; Associação de Combate ao Câncer. Araújo Jorge Hospital. Goiás. BR
  • Kipnis, André; Federal University of Goiás. Institute of Tropical Pathology and Public Health.
  • Junqueira-Kipnis, Ana Paula; Federal University of Goiás. Institute of Tropical Pathology and Public Health.
Braz. j. infect. dis ; 12(5): 447-452, Oct. 2008. ilus, tab
Article in English | LILACS | ID: lil-505362
Responsible library: BR1.1
ABSTRACT
Extensively drug-resistant tuberculosis (XDR-TB) is an emerging health problem that threatens tuberculosis (TB) control worldwide, since suitable treatment for this disease has not yet been found. We report a case of secondary pulmonary XDR-TB in a 54-year-old, HIV-negative male from Goiânia, Brazil. The patient had long-standing pulmonary tuberculosis (nine years) with extensive bilateral lung damage and had been treated with multiple antituberculosis drugs (self-administered) before XDR-TB diagnosis. The strain of Mycobacterium tuberculosis was resistant to R- rifampicin, H-isoniazid, E-ethambutol, Eto-ethionamide, Ofx-ofloxacin, and Am-amikacin. This patient died with multiple organ failure due to sepsis secondary to bacterial pneumonia.
Subject(s)

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Full text: Available Collection: International databases Health context: SDG3 - Health and Well-Being / Neglected Diseases / SDG3 - Target 3.3 End transmission of communicable diseases / SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases Health problem: Target 3.3: End transmission of communicable diseases / Neglected Diseases / Tuberculosis / Antimicrobial Resistance / Tuberculosis / Other Respiratory Diseases Database: LILACS Main subject: Tuberculosis, Pulmonary / Extensively Drug-Resistant Tuberculosis / Mycobacterium tuberculosis / Antitubercular Agents Limits: Humans / Male Language: English Journal: Braz. j. infect. dis Journal subject: Communicable Diseases Year: 2008 Document type: Article Affiliation country: Brazil Institution/Affiliation country: Associação de Combate ao Câncer/BR
Fulltext
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Full text: Available Collection: International databases Health context: SDG3 - Health and Well-Being / Neglected Diseases / SDG3 - Target 3.3 End transmission of communicable diseases / SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases Health problem: Target 3.3: End transmission of communicable diseases / Neglected Diseases / Tuberculosis / Antimicrobial Resistance / Tuberculosis / Other Respiratory Diseases Database: LILACS Main subject: Tuberculosis, Pulmonary / Extensively Drug-Resistant Tuberculosis / Mycobacterium tuberculosis / Antitubercular Agents Limits: Humans / Male Language: English Journal: Braz. j. infect. dis Journal subject: Communicable Diseases Year: 2008 Document type: Article Affiliation country: Brazil Institution/Affiliation country: Associação de Combate ao Câncer/BR