Transgenic lettuce seedlings carrying hepatitis B virus antigen HBsAg
Braz. j. infect. dis
; 12(6): 469-471, Dec. 2008. ilus
Article
in English
| LILACS
| ID: lil-507443
Responsible library:
BR1.1
ABSTRACT
The obtainment of transgenic edible plants carrying recombinant antigens is a desired issue in search for economic alternatives viewing vaccine production. Here we report a strategy for genetic transformation of lettuce plants (Lactuca sativa L.) using the surface antigen HBsAg of hepatitis B virus. Transgenic lettuce seedlings were obtained through the application of a regulated balance of plant growth regulators. Genetic transformation process was acquired by cocultivation of cotyledons with Agrobacterium tumefaciens harboring the recombinant plasmid. It is the first description of a lettuce Brazilian variety "Vitória de Verão" genetically modified.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Plants, Genetically Modified
/
Hepatitis B Vaccines
/
Lactuca
/
Hepatitis B Surface Antigens
Language:
English
Journal:
Braz. j. infect. dis
Journal subject:
Communicable Diseases
Year:
2008
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
State University of North Fluminense/BR
/
UNESP/BR