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Soroprevalência da hepatite C em pacientes com esquistossomose / Seroprevalence of hepatitis C in schistosomiasis patients
Silva, Jéfferson Luis de Almeida; Coêlho, Maria Rosângela Cunha Duarte; Souza, Veridiana Sales Barbosa de; Domingues, Ana Lúcia Coutinho.
Affiliation
  • Silva, Jéfferson Luis de Almeida; Universidade Federal de Pernambuco. Laboratório de Imunopatologia Keizo Asami. Recife. BR
  • Coêlho, Maria Rosângela Cunha Duarte; Universidade Federal de Pernambuco. Laboratório de Imunopatologia Keizo Asami. Recife. BR
  • Souza, Veridiana Sales Barbosa de; Universidade Federal de Pernambuco. Laboratório de Imunopatologia Keizo Asami. Recife. BR
  • Domingues, Ana Lúcia Coutinho; Universidade Federal de Pernambuco. Centro de Ciências da Saúde. Departamento de Medicina Clínica. Recife. BR
Rev. para. med ; 22(1): 27-32, Jan.-Mar. 2008. tab
Article in Portuguese | LILACS | ID: lil-510307
Responsible library: BR3.1
RESUMO

Objetivo:

pesquisar o anti-HCV em portadores de esquistossomose mansônica.

Método:

foram testadas amostras de soro de 184 pacientes atendidos no Ambulatório de Gastroenterologia do Hospital das Clínicas da Universidade Federal de Pemambuco, empregando-se o ELISA de 3ª geração (Wiener) de acordo com as instruções do fabricante.

Resultados:

detectou-se resultado positivo para o anti-HCV em 22 pacientes, revelando uma prevalência de 11,9%. Entre os co-infectados de ambos os sexos, 90,9% apresentaram aforma hepatoesplênica da esquistossomose e 54,5% já havia recebido transfusão sangüínea. Analisando-se o passado de endoscopia digestiva, todos os pacientes co-infectados do sexo masculino e 81,8% do sexo feminino foram submetidos ao procedimento.

Conclusões:

foi alta a prevalência do anti-HCV em portadores de esquistossomose, a história de transfusão sangüínea e principalmente endoscopia digestiva mostraram-se como prováveis fontes de infecção.
ABSTRACT

Objective:

to research the anti-HCV antibody prevalence in patients diagnosed with mansonic schistosomiasis. Methos serum sample of 184 patients attending the Gastroenterology Clinics of Hospital das Clínicas da Universidade Federal de Pernambuco were tested for anti-HCV by a third generation ELISA (Wiener@) according to the manufacturer's instructions.

Results:

a positive resultfor anti-HCV was detected in 22 patients, establishing a prevalence of 11.9%. Among coinfected ofboth sexes, 90.9% had presented hepatosplenic schistosomiasis and 54.5% had had blood transfusion. Analyzing the endoscopy in the past, all coinfected male patients and 81.8% of coinfected females had undergone endoscopy previously.

Conclusions:

the prevalence of anti-HCV in schistosomiasis patients was high. B/ood transfusion and particularly digestive endoscopy were shown as probable infection sources.
Subject(s)

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Collection: International databases Health context: Neglected Diseases Health problem: Helminthiasis / Neglected Diseases / Schistosomiasis / Zoonoses Database: LILACS Main subject: Schistosomiasis mansoni / Cross-Sectional Studies / Hepatitis C / Hepatitis C Antibodies Type of study: Observational study / Prevalence study / Risk factors Limits: Adult / Female / Humans / Male Country/Region as subject: South America / Brazil Language: Portuguese Journal: Rev. para. med Journal subject: Medicine Year: 2008 Document type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal de Pernambuco/BR
Search on Google
Collection: International databases Health context: Neglected Diseases Health problem: Helminthiasis / Neglected Diseases / Schistosomiasis / Zoonoses Database: LILACS Main subject: Schistosomiasis mansoni / Cross-Sectional Studies / Hepatitis C / Hepatitis C Antibodies Type of study: Observational study / Prevalence study / Risk factors Limits: Adult / Female / Humans / Male Country/Region as subject: South America / Brazil Language: Portuguese Journal: Rev. para. med Journal subject: Medicine Year: 2008 Document type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal de Pernambuco/BR
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