Clinical, bacteriological and immunological follow-up of household contacts of leprosy patients from a post-elimination area - Antioquia, Colombia
Mem. Inst. Oswaldo Cruz
; 104(6): 935-936, Sept. 2009.
Article
in En
| LILACS
| ID: lil-529567
Responsible library:
BR1.1
ABSTRACT
Follow-up of the household contacts (HHC) of leprosy patients is still the best strategy for early detection of leprosy. HHC from a post-elimination region of Colombia studied in 2001-2002 were re-contacted in 2007. They were tested at both times by clinical examination, bacillary index (BI), PCR from a slit skin smear (SSS) and anti PGL-1 IgM titres. Thirty-two of 61 HHC (52 percent) were re-contacted. Nine HHC (28 percent) showed sero-conversion and one had a skin lesion (BI negative, nested PCR positive). Periodic evaluation of HHC can contribute to the detection of infected HHC as well as new and early leprosy cases.
Key words
Full text:
1
Collection:
01-internacional
Database:
LILACS
Main subject:
Immunoglobulin G
/
Contact Tracing
/
Leprosy
/
Antibodies, Bacterial
/
Mycobacterium leprae
Type of study:
Etiology_studies
/
Risk_factors_studies
/
Screening_studies
Limits:
Adolescent
/
Adult
/
Aged
/
Child
/
Female
/
Humans
/
Male
Country/Region as subject:
America do sul
/
Colombia
Language:
En
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
MEDICINA TROPICAL
/
PARASITOLOGIA
Year:
2009
Document type:
Article
Affiliation country:
Colombia
Country of publication:
Brazil