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Complexo miointimal das carótidas comum e interna em portadores de esquistossomose mansônica hepatoesplênica / Intima-media thickness of common and internal carotid arteries in patients with hepatosplenic schistosomiasis mansoni
Guimarães, André Valença; Brandt, Carlos Teixeira; Ferraz, Adriana.
Affiliation
  • Guimarães, André Valença; s.af
  • Brandt, Carlos Teixeira; The University of Liverpool. GB
  • Ferraz, Adriana; s.af
Rev. Col. Bras. Cir ; 36(4): 292-299, jul.-ago. 2009. tab
Article in Portuguese | LILACS | ID: lil-531021
Responsible library: BR1.1
RESUMO

OBJETIVO:

Avaliar a espessura do complexo miointimal (IMT) das carótidas comum e interna, em portadores de esquistossomose hepatoesplênica (EHE) não tratados cirurgicamente, já submetidos a cirurgia para descompressão do sistema porta por esplenectomia e ligadura da veia gástrica esquerda, e comparar com volutários de condições sócio-econômico-ambientais similares, não portadores de esquistossomose.

MÉTODOS:

Utilizando aparelho de ultra-som Doppler de 7,5MHz foram mensurados os IMT de três grupos de voluntários, de ambos os gêneros, com idades que variaram de 20 a 60 anos, sendo avaliados os IMT máximos, IMT médios, IMT mínimos e seus desvios-padrão, das carótidas comuns e internas e feitas as comparações entre os grupos e suas associações com fatores de risco idade, hipertensão arterial e tabagismo.

RESULTADOS:

Não houve diferença significante na média dos IMT, entre os lados direito e esquerdo e nem entre os grupos. Nos pacientes tratados cirurgicamente, assim como nos indivíduos-controle confirmou-se a associação, já conhecida, com os fatores de risco para aterosclerose (idade, hipertensão arterial e tabagismo). Contudo, não se observou este comportamento nos pacientes não operados.

CONCLUSÃO:

A EHE sem tratamento cirúrgico parece conferir "alguma proteção" contra a aterogênese em seres humanos; todavia, os achados não dão suporte definitivo a esta hipótese.
ABSTRACT

OBJECTIVE:

To evaluate the intima-media thickness (IMT) of common and internal carotid arteries in patients with hepatosplenic schistomiasis mansoni and those who underwent portal decompression surgery (splenectomy and left gastric artery ligature). Both groups were compared with a health volunteer control group, living in the same social-economic-environmental conditions. MEHTODS An ultrasound Doppler with a 7.5 MHz probe was used. The IMT was measured in the three groups with 20 individuals each, of both gender, with ages ranging from 20 to 60 years. The mean and standard deviations of common and internal carotid arteries maxIMT, medIMT, minIMT were assessed. Risk factors age, systemic arterial hypertension and cigarette smoking were investigated as regard to IMT measurements.

RESULTS:

There were no statistical differences in IMT between right and left side, and among surgical, non-surgical and control groups. The surgical treated patients and controls showed correlation to known atherosclerotic risk factors age, hypertension and cigarette smoking. However, non-surgically treated patients did not present the same correlation. CONLCUSION It is tempting to believe that non-operated schistosomotic patients may have "some protection" against atherogenesis in human beings; however, the data do not lend full support to this hypothesis.
Subject(s)

Full text: Available Collection: International databases Health context: SDG3 - Health and Well-Being / Neglected Diseases Health problem: Target 3.3: End transmission of communicable diseases / Helminthiasis / Neglected Diseases / Schistosomiasis / Zoonoses Database: LILACS Main subject: Splenic Diseases / Schistosomiasis mansoni / Carotid Arteries / Tunica Media / Tunica Intima / Atherosclerosis / Liver Diseases, Parasitic Type of study: Observational study / Risk factors Limits: Adult / Female / Humans / Male Language: Portuguese Journal: Rev. Col. Bras. Cir Journal subject: CIRURGIA GERAL Year: 2009 Document type: Article Affiliation country: United kingdom Institution/Affiliation country: The University of Liverpool/GB
Full text: Available Collection: International databases Health context: SDG3 - Health and Well-Being / Neglected Diseases Health problem: Target 3.3: End transmission of communicable diseases / Helminthiasis / Neglected Diseases / Schistosomiasis / Zoonoses Database: LILACS Main subject: Splenic Diseases / Schistosomiasis mansoni / Carotid Arteries / Tunica Media / Tunica Intima / Atherosclerosis / Liver Diseases, Parasitic Type of study: Observational study / Risk factors Limits: Adult / Female / Humans / Male Language: Portuguese Journal: Rev. Col. Bras. Cir Journal subject: CIRURGIA GERAL Year: 2009 Document type: Article Affiliation country: United kingdom Institution/Affiliation country: The University of Liverpool/GB
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