Aportes de la epigenética en la comprensión del desarrollo del ser humano: [revisión] / Contribution of epigenetics to understand human development: [review]
Rev. méd. Chile
; 138(3): 366-372, mar. 2010.
Article
in Spanish
| LILACS
| ID: lil-548175
Responsible library:
BR1.1
ABSTRACT
Epigenetics refers to the study of how genes produce their effect on the phenotype of the organism. This article is a review on the scope and importance of recently discovered epigenetic mechanisms on human development and their relationship to perinatal epidemiological issues. It shows a general view and present concepts about epigenetics and its contribution to the comprehension of several physiologic and pathological conditions of human beings. Secondly, it analyzes the evidence coming from epidemiological and animal studies, about the influence of events that occur in the perinatal and early postnatal periods on adult life and the possible epigenetic mechanisms involved. Lastly, it underscores the implications ofthese results of future research and the design of public policies that take into account the importance of events in early life in thefuture development of individuals.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Prenatal Exposure Delayed Effects
/
Epigenesis, Genetic
/
Human Development
Limits:
Animals
/
Female
/
Humans
/
Pregnancy
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2010
Document type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Pontificia Universidad Católica de Chile/CL