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Clinical and epidemiological characterization of dengue hemorrhagic fever cases in northeastern, Brazil / Caracterização clínica e epidemiológica dos casos de dengue hemorrágica no nordeste do Brasil
Cavalcanti, Luciano Pamplona de Góes; Coelho, Ivo Castelo Branco; Vilar, Dina Cortez Lima Feitosa; Holanda, Susana Glória Silveira; Escóssia, Kiliana Nogueira Farias da; Souza-Santos, Reinaldo.
Affiliation
  • Cavalcanti, Luciano Pamplona de Góes; Federal University of Ceará. Graduate Program in Medical Sciences. Fortaleza. BR
  • Coelho, Ivo Castelo Branco; Federal University of Ceará. Pathology Department. Fortaleza. BR
  • Vilar, Dina Cortez Lima Feitosa; Secretaria da Saúde do Ceará. Epidemiology Core. Fortaleza. BR
  • Holanda, Susana Glória Silveira; Secretaria da Saúde do Ceará. Epidemiology Core. Fortaleza. BR
  • Escóssia, Kiliana Nogueira Farias da; Secretaria da Saúde do Ceará. Epidemiology Core. Fortaleza. BR
  • Souza-Santos, Reinaldo; National School of Public Health. Rio de Janeiro. BR
Rev. Soc. Bras. Med. Trop ; 43(4): 355-358, jul.-ago. 2010. graf, tab
Article in English | LILACS | ID: lil-555995
Responsible library: BR1.1
ABSTRACT

INTRODUCTION:

The dengue hemorrhagic dengue (DHF) remains an important public health problem in Brazil. The objective of this study was to analyze the epidemiological characteristics of DHF cases during the 2003 epidemic in Ceará.

METHODS:

Suspected DHF cases with onset of symptoms between January and December 2003 were investigated.

RESULTS:

37,964 classic dengue cases and 291 DHF cases were reported. Among the cases discarded, 75.5 percent were serologically positive but did not meet the criteria recommended by the World Health Organization (WHO). The DHF patients' median age was 30 years (2 - 88). Among the hemorrhagic manifestations, petechiae were the most (32.6 percent) frequent. Cases of gastrointestinal bleeding, ascites, pericardial pleural effusion, hepatomegaly, hypotension and shock showed higher risk of progression to death (p <0.05).

CONCLUSIONS:

The introduction of a new serotype (DENV-3) in Ceará, which encountered a susceptible population and high vector density, may have been the primary agent responsible for the magnitude of the epidemic. Timely and appropriate medical care, along with an organized care structure are essential for reducing its lethality.
RESUMO

INTRODUÇÃO:

A febre hemorrágica do dengue (FHD) permanece como um importante problema de saúde pública no Brasil. O objetivo deste estudo é analisar os aspectos epidemiológicos dos casos de dengue hemorrágico durante a epidemia de 2003, no Ceará.

MÉTODOS:

Foram investigados os casos suspeitos de FHD, com início de sintomas no período de janeiro a dezembro de 2003.

RESULTADOS:

Foram reportados 37.964 casos de dengue clássica, com 291 casos de FHD. Entre os casos descartados, 75,5 por cento apresentaram sorologia positiva, mas não preenchem os critérios recomendados pela Organização Mundial de Saúde. A mediana de idade dos pacientes com FHD foi de 30 anos (2 - 88). Para manifestações hemorrágicas, as petéquias com 32,6 por cento foram as mais frequentes. Os casos de hemorragia digestiva, ascite, derrame pleural e pericárdico, hepatomegalia, hipotensão e choque apresentaram maior risco de progressão para óbito (p <0,05).

CONCLUSÕES:

A introdução de um novo sorotipo (DENV-3) no Ceará, encontrando a população suscetível e a alta densidade do vetor podem ter sido os principais responsáveis pela magnitude da epidemia. A atenção médica oportuna e adequada, bem como uma estrutura organizada de cuidado aos pacientes são indispensáveis para reduzir a letalidade.
Subject(s)

Full text: Available Collection: International databases Health context: Sustainable Health Agenda for the Americas / SDG3 - Health and Well-Being / Neglected Diseases / SDG3 - Target 3.3 End transmission of communicable diseases Health problem: Goal 8: Outbreaks, emergencies and disasters / Target 3.8 Achieve universal access to health / Target 3.3: End transmission of communicable diseases / Target 3.2: Reduce avoidable death in newborns and children under 5 / Dengue / Neglected Diseases / Dengue Database: LILACS Main subject: Disease Outbreaks / Severe Dengue Type of study: Etiology study / Risk factors Limits: Adolescent / Adult / Aged / Aged, 80 and over / Child / Child, preschool / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Rev. Soc. Bras. Med. Trop Journal subject: Tropical Medicine Year: 2010 Document type: Article Affiliation country: Brazil Institution/Affiliation country: Federal University of Ceará/BR / National School of Public Health/BR / Secretaria da Saúde do Ceará/BR
Full text: Available Collection: International databases Health context: Sustainable Health Agenda for the Americas / SDG3 - Health and Well-Being / Neglected Diseases / SDG3 - Target 3.3 End transmission of communicable diseases Health problem: Goal 8: Outbreaks, emergencies and disasters / Target 3.8 Achieve universal access to health / Target 3.3: End transmission of communicable diseases / Target 3.2: Reduce avoidable death in newborns and children under 5 / Dengue / Neglected Diseases / Dengue Database: LILACS Main subject: Disease Outbreaks / Severe Dengue Type of study: Etiology study / Risk factors Limits: Adolescent / Adult / Aged / Aged, 80 and over / Child / Child, preschool / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Rev. Soc. Bras. Med. Trop Journal subject: Tropical Medicine Year: 2010 Document type: Article Affiliation country: Brazil Institution/Affiliation country: Federal University of Ceará/BR / National School of Public Health/BR / Secretaria da Saúde do Ceará/BR
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