Ensayo clínico prágmatico en trauma: el estudio CRASH-2 en el Perú / Pragmatic clinical trial in trauma: CRASH 2 trial in Perú
Rev. peru. med. exp. salud publica
; 25(1): 138-143, ene.-mar. 2008. tab
Article
in Spanish
| LILACS, LIPECS
| ID: lil-564675
Responsible library:
PE1.1
RESUMEN
El estudio CRASH-2 es un ensayo clínico pragmático que busca evaluar la eficacia de un antifibrinolítico de bajo costoy ampliamente disponible para la prevención de mortalidad y sangrado en pacientes con trauma. En este artículo presentamos algunos conceptos relacionados a la magnitud del problema y la necesidad de investigación en trauma en el contexto peruano. Asimismo se discute las bases teóricas y practicas del ensayo CRASH-2 así como la experiencia peruana hasta el momento.
ABSTRACT
CRASH-2 is a pragmatic clinical trial which evaluates the efficacy of a widely available, low cost antifibrinolytic for the prevention of mortality and bleeding in patients with trauma. In this article we present some issues related to the magnitude of the problem as well as the need for research in trauma relevant to the Peruvian context. The rationale for the CRASH-2 trial and the Peruvian experience up to date are also discussed.
Full text:
Available
Collection:
National databases
/
Peru
Health context:
SDG3 - Health and Well-Being
Health problem:
Target 3.6: Reduce deaths and the trauma caused by road accidents
Database:
LILACS
/
LIPECS
Main subject:
Tranexamic Acid
/
Accidents, Traffic
/
Clinical Trials as Topic
/
Antifibrinolytic Agents
Limits:
Humans
Country/Region as subject:
South America
/
Peru
Language:
Spanish
Journal:
Rev. peru. med. exp. salud publica
Year:
2008
Document type:
Article
Institution/Affiliation country:
Clínica Santa Ana/PE
/
Hospital Dos de Mayo/PE
/
Hospital III EsSalud/PE
/
Hospital José Cayetano Heredia/PE
/
Hospital Municipal los Olivos/PE
/
Hospital Nacional Arzobispo Loayza/PE
/
Hospital Nacional Cayetano Heredia/PE
/
Hospital Nacional Hípólito Unanue/PE
/
Hospital Regional Docente/PE
/
Hospital de Apoyo de Sullana/PE