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Molecular epidemiology of HIV-1 clades in Southern Brazil
Raboni, Sonia Mara; Almeida, Sérgio Monteiro de; Rotta, Indianara; Ribeiro, Cléa Elisa Lopes; Rosario, Debra; Vidal, Luine Rosele; Nogueira, Meri Bordignon; Riedel, Maristela; Winhescki, Maria da Graça; Ferreira, Kátia Antunes; Ellis, Ronald.
Affiliation
  • Raboni, Sonia Mara; s.af
  • Almeida, Sérgio Monteiro de; s.af
  • Rotta, Indianara; s.af
  • Ribeiro, Cléa Elisa Lopes; s.af
  • Rosario, Debra; s.af
  • Vidal, Luine Rosele; s.af
  • Nogueira, Meri Bordignon; s.af
  • Riedel, Maristela; s.af
  • Winhescki, Maria da Graça; s.af
  • Ferreira, Kátia Antunes; s.af
  • Ellis, Ronald; s.af
Mem. Inst. Oswaldo Cruz ; 105(8): 1044-1049, Dec. 2010. ilus, graf, mapas, tab
Article in English | LILACS | ID: lil-570677
Responsible library: BR1.1
ABSTRACT
Human immunodeficiency virus (HIV) clades B and C account for more than 60 percent of the HIV-1 infections worldwide. In this paper, we describe the profiles of patients infected with subtypes of HIV-1 from the state of Paraná, Southern Brazil, and correlate them with demographic and epidemiological findings. A retrospective analysis of HIV cases reported from 1999-2007 was also performed. Data from 293 patients were reviewed and 245 were older than 13 (58 percent female). The distribution of clades was as follows B 140 (57 percent), C 67 (23 percent), F 24 (10 percent) and mosaic or unique recombinant forms (URFs) 24 (10 percent). Of the 48 patients younger than 13 years of age (62.5 percent male), vertical transmission occurred in 46 and the distribution of clades was as follows B 14 (29 percent), C 24 (50 percent), F 7 (15 percent) and URFs 6 (13 percent). There was no significant difference in mortality between HIV-1 subtypes. In both groups, patients infected with clade C tended to have higher rates of injection drug use exposure risk.
Subject(s)


Full text: Available Collection: International databases Database: LILACS Main subject: HIV Infections / HIV-1 Type of study: Etiology study / Observational study / Prevalence study / Risk factors / Screening study Limits: Adolescent / Adult / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Mem. Inst. Oswaldo Cruz Journal subject: Tropical Medicine / Parasitology Year: 2010 Document type: Article

Full text: Available Collection: International databases Database: LILACS Main subject: HIV Infections / HIV-1 Type of study: Etiology study / Observational study / Prevalence study / Risk factors / Screening study Limits: Adolescent / Adult / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Mem. Inst. Oswaldo Cruz Journal subject: Tropical Medicine / Parasitology Year: 2010 Document type: Article
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