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Infección del torrente circulatorio en una unidad de neonatología de Medellín-Colombia, 2008-2009 / Bloodstream infection in a neonatology unit of Medellín-Colombia, 2008-2009
Hoyos O, Alvaro; Suarez G, Margarita; Massaro C, Mónica; Ortiz M, Gloría; Aguirre C, José; Uribe M, Andrés.
Affiliation
  • Hoyos O, Alvaro; Clínica Universitaria Bolivariana. Medellín. CO
  • Suarez G, Margarita; Universidad Pontificia Bolivariana. Facultad de Medicina. CO
  • Massaro C, Mónica; Universidad Pontificia Bolivariana. Facultad de Medicina. CO
  • Ortiz M, Gloría; Clínica Universitaria Bolivariana. Medellín. CO
  • Aguirre C, José; Clínica Universitaria Bolivariana. Medellín. CO
  • Uribe M, Andrés; Clínica Universitaria Bolivariana. Medellín. CO
Rev. chil. infectol ; Rev. chil. infectol;27(6): 491-498, dic. 2010. tab
Article in Es | LILACS | ID: lil-572911
Responsible library: CL1.1
ABSTRACT
Bloodstream infection (BSI) is one of the main causes of sepsis and death in newborns. The relative importance of nosocomial and non-nosocomial agents in developing countries is not clear. We conducted a prospective study of newborns hospitalized with a first episode of BSI in order to classify it as early, late or nosocomial, describe the clinical and microbiological charateristics, and explore risk factors between hospital-acquired vs commu-nity-acquiered BSI (HA-BSI vs CA-BSI). Twenty-seven newborns with a first episode of BSI were identified. Streptococcus agalactiae and coagulase negative Staphylococcus were the main agents in CA-BSI and HA-BSI, respectively. The only significant intrinsic risk factor between HA-BSI and CA-BSI was gestational age. The frequent finding of S. agalactiae warrants routine screening and prophylaxis in pregnant women. The risk factors for HA-BSI were mostly extrinsic, and thus, susceptible of being modified.
RESUMEN
La infección del torrente circulatorio (ITC) es una de las principales causas de sepsis y muerte neonatal. Su etiología en países en vía de desarrollo, entre agentes no nosocomiales vs nosocomiales no está suficientemente esclarecida. Estudio prospectivo que incluyó neonatos hospitalizados que presentaron un primer hemocultivo positivo, con el propósito de describir características clínicas, microbiológicas, clasificar la ITC en temprana, tardía y nosocomial, y explorar factores de riesgo entre ITC adquirida en la comunidad vs ITC adquirida en el hospital (ITC-AC vs ITC-AH). Se identificaron 27 neonatos con un primer episodio de ITC. Streptococcus agalactiae y Staphylococcus coagulasa negativa fueron los principales agentes en ITC-AC e ITC-AH, respectivamente. El factor de riesgo intrínseco que mostró una diferencia significativa entre ITC-AC vs. ITC-AH fue la edad gestacional. La presencia de S. agalactiae permite plantear el tamizaje y profilaxis a la gestante. Los factores de riesgo para ITC-AH fueron en su mayoría extrínsecos, es decir, susceptibles de ser modificados.
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Full text: 1 Collection: 01-internacional Database: LILACS Main subject: Cross Infection / Gram-Positive Bacterial Infections / Gram-Negative Bacterial Infections / Bacteremia / Community-Acquired Infections Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male / Newborn Country/Region as subject: America do sul / Colombia Language: Es Journal: Rev. chil. infectol Journal subject: DOENCAS TRANSMISSIVEIS Year: 2010 Document type: Article Affiliation country: Colombia Country of publication: Chile

Full text: 1 Collection: 01-internacional Database: LILACS Main subject: Cross Infection / Gram-Positive Bacterial Infections / Gram-Negative Bacterial Infections / Bacteremia / Community-Acquired Infections Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male / Newborn Country/Region as subject: America do sul / Colombia Language: Es Journal: Rev. chil. infectol Journal subject: DOENCAS TRANSMISSIVEIS Year: 2010 Document type: Article Affiliation country: Colombia Country of publication: Chile