Occurrence of yeasts, pseudomonads and enteric bacteria in the oral cavity of patients undergoing head and neck radiotherapy
Braz. j. microbiol
; 42(3): 1047-1055, July-Sept. 2011. tab
Article
in English
| LILACS
| ID: lil-607534
Responsible library:
BR32.1
ABSTRACT
The aim of this study was to evaluate the occurrence of yeasts, pseudomonads and enteric bacteria in the oral cavity of patients undergoing radiotherapy (RT) for treatment of head and neck cancer. Fifty patients receiving RT were examined before, during and 30 days after RT. Saliva, mucosa, and biofilm samples were collected and microorganisms were detected by culture and polymerase chain reaction (PCR). The most prevalent yeasts in patients submitted to RT were Candida albicans, C. tropicalis, C. krusei, C. glabrata and C. parapsilosis. Citrobacter, Enterobacter, Enterococcus, Klebsiella, Proteus, and Pseudomonas were the most frequently cultivated bacteria. Before RT, targeted bacteria were cultivated from 22.2 percent of edentulous patients and 16.6 percent of dentate patients; 30 days after RT, these microorganisms were recovered from 77.8 percent edentulous and 46.8 percent dentate patients. By PCR, these microorganisms were detected from all edentulous patients, 78.1 percent of dentate patients. The presence of Gram-negative enteric roads and fungi was particularly frequent in patients presenting mucositis level III or IV. Modifications in the oral environment due to RT treatment seem to facilitate the colonization of oral cavity by members of family Enterobacteriaceae, genera Enterococcus and Candida.
Full text:
Available
Collection:
International databases
Health context:
Neglected Diseases
Health problem:
Neglected Diseases
/
Zoonoses
Database:
LILACS
Main subject:
Radiotherapy
/
Surgical Procedures, Operative
/
Yeasts
/
In Vitro Techniques
/
Polymerase Chain Reaction
/
Enterobacteriaceae
/
Enterobacteriaceae Infections
/
Mouth
/
Noma
Type of study:
Evaluation study
/
Prevalence study
/
Risk factors
Limits:
Humans
Language:
English
Journal:
Braz. j. microbiol
Journal subject:
Microbiology
Year:
2011
Document type:
Article
/
Project document
Affiliation country:
Brazil
/
Nigeria
Institution/Affiliation country:
Universidade Estadual Paulista/BR
/
Universidade de São Paulo/BR
/
University of Lagos/NG