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Effect of calcitonin on hepatic drug metabolism
Godinho, A. F; Cavalcante, G. J. S; Machado, M. G; Faria, T. F. A; Gil, T. C. P; Coutinho, Rilza Beatriz G. de A; Garcia, C.
Braz. j. med. biol. res ; 21(4): 851-3, 1988. ilus, tab
Article in English | LILACS | ID: lil-60809
Responsible library: BR26.1
ABSTRACT
A single dose of calcitonin (150 mIU/100g body weight, sc) produced a significant decrease in liver antipyrine hydroxylase and aminopyrine demethylase activities. By contrast, pentobarbital sleeping time was not altered by calcitonin treatment. The present results indicate that acute calcitonin administration depresses the metabolism of substrates of the mixed function oxidase system of rat liver
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Collection: International databases Database: LILACS Main subject: Sleep / Calcitonin / Mixed Function Oxygenases / Liver Limits: Animals Language: English Journal: Braz. j. med. biol. res Journal subject: Biology / Medicine Year: 1988 Document type: Article / Congress and conference
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Collection: International databases Database: LILACS Main subject: Sleep / Calcitonin / Mixed Function Oxygenases / Liver Limits: Animals Language: English Journal: Braz. j. med. biol. res Journal subject: Biology / Medicine Year: 1988 Document type: Article / Congress and conference