Your browser doesn't support javascript.
loading
Perinatal morbidity and mortality associated with chlamydial infection: a meta-analysis study
Silva, Maria José Penna Maisonnette de Attayde; Florêncio, Gilzandra Lira Dantas; Gabiatti, José Roberto Erbolato; Amaral, Rose Luce do; Eleutério Júnior, José; Gonçalves, Ana Katherine da Silveira.
Affiliation
  • Silva, Maria José Penna Maisonnette de Attayde; Universidade Federal do Rio Grande do Norte. Postgraduate Program in Health Sciences.
  • Florêncio, Gilzandra Lira Dantas; Universidade Federal do Rio Grande do Norte. Postgraduate Program in Health Sciences.
  • Gabiatti, José Roberto Erbolato; Universidade Estadual de Campinas. Faculdade de Ciências Médicas. Tocoginecology Department. BR
  • Amaral, Rose Luce do; UNICAMP.
  • Eleutério Júnior, José; Universidade Federal do Ceará. BR
  • Gonçalves, Ana Katherine da Silveira; UFRN. BR
Braz. j. infect. dis ; 15(6): 533-539, Nov.-Dec. 2011. tab
Article in English | LILACS | ID: lil-610523
Responsible library: BR1.1
ABSTRACT

OBJECTIVE:

To evaluate the effect of Chlamydia trachomatis infection during pregnancy on perinatal morbidity and mortality.

METHODS:

Systematic review and meta-analysis in an electronic database and manual, combining high sensitivity specific descriptors seeking to answer the research objective. The articles considered to be of high methodological quality (score above 6 on the Newcastle-Ottawa Scale) were assessed by meta-analysis.

RESULTS:

Summary estimates of 12 studies were calculated by means of Mantel-Haenszel test with 95 percent confidence interval. It was observed that Chlamydia infection during pregnancy increased risk of preterm labor (relative risk (RR) = 1.35 [1.11, 1.63]), low birth weight (RR = 1.52 [1.24, 1.87]) and perinatal mortality (RR = 1.84 [1.15, 2.94]). No evidence of increased risk was associated with Chlamydia infection in regard to premature rupture of membranes (RR = 1.13 [0.95, 1.34]), abortion and postpartum endometritis (RR = 1.20 [0.65, 2.20] and 0.89 [0.49, 1.61] respectively).

CONCLUSION:

The diagnosis and treatment of Chlamydia cervicitis during pregnancy can reduce perinatal morbidity and mortality associated with this infection. However, clinical trials are needed to confirm these findings.
Subject(s)


Full text: Available Collection: International databases Health context: SDG3 - Health and Well-Being / SDG3 - Target 3.2 Reduce avoidable death in newborns and children under 5 Health problem: Target 3.2: Reduce avoidable death in newborns and children under 5 / Neonatal Healthcare Database: LILACS Main subject: Pregnancy Complications, Infectious / Chlamydia Infections / Uterine Cervicitis / Perinatal Mortality Type of study: Diagnostic study / Etiology study / Practice guideline / Risk factors / Systematic review Limits: Female / Humans / Infant, Newborn / Pregnancy Language: English Journal: Braz. j. infect. dis Journal subject: Communicable Diseases Year: 2011 Document type: Article / Project document Affiliation country: Brazil Institution/Affiliation country: UFRN/BR / Universidade Estadual de Campinas/BR / Universidade Federal do Ceará/BR

Full text: Available Collection: International databases Health context: SDG3 - Health and Well-Being / SDG3 - Target 3.2 Reduce avoidable death in newborns and children under 5 Health problem: Target 3.2: Reduce avoidable death in newborns and children under 5 / Neonatal Healthcare Database: LILACS Main subject: Pregnancy Complications, Infectious / Chlamydia Infections / Uterine Cervicitis / Perinatal Mortality Type of study: Diagnostic study / Etiology study / Practice guideline / Risk factors / Systematic review Limits: Female / Humans / Infant, Newborn / Pregnancy Language: English Journal: Braz. j. infect. dis Journal subject: Communicable Diseases Year: 2011 Document type: Article / Project document Affiliation country: Brazil Institution/Affiliation country: UFRN/BR / Universidade Estadual de Campinas/BR / Universidade Federal do Ceará/BR
...