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Sodium fluoride does not alter sperm production or sperm morphology in rats
Chioca, Lea Rosa; Müller, Juliane Centeno; Boareto, Ana Cláudia; Andreatini, Roberto; Dalsenter, Paulo Roberto.
Affiliation
  • Chioca, Lea Rosa; Universidade Federal do Paraná. Departamento de Farmacologia. Curitiba. BR
  • Müller, Juliane Centeno; Universidade Federal do Paraná. Departamento de Farmacologia. Curitiba. BR
  • Boareto, Ana Cláudia; Universidade Federal do Paraná. Departamento de Farmacologia. Curitiba. BR
  • Andreatini, Roberto; Universidade Federal do Paraná. Departamento de Farmacologia. Curitiba. BR
  • Dalsenter, Paulo Roberto; Universidade Federal do Paraná. Departamento de Farmacologia. Curitiba. BR
Braz. arch. biol. technol ; Braz. arch. biol. technol;55(2): 257-262, Mar.-Apr. 2012. tab
Article in En | LILACS | ID: lil-622705
Responsible library: BR1.1
ABSTRACT
The aim of the present study was to evaluate the effects of sodium fluoride (NaF) on the male reproductive system. Adult male rats were exposed to NaF in drinking water for 30 days at three concentrations 1.54 (control, tap water), 50 and 100 ppm. Body and organ weights, daily sperm production, sperm number and morphology were investigated. No difference was observed on the sperm number and morphology among the groups, as well as body weight and organ absolute and relative weights. Overall, despite the presence of a mild degree of dental fluorosis in the higher dose group, the results indicated that exposure to NaF at the doses used in the present study did not adversely affect sperm production and morphology of male rats.
Key words

Full text: 1 Collection: 01-internacional Database: LILACS Language: En Journal: Braz. arch. biol. technol Journal subject: BIOLOGIA Year: 2012 Document type: Article Affiliation country: Brazil Country of publication: Brazil

Full text: 1 Collection: 01-internacional Database: LILACS Language: En Journal: Braz. arch. biol. technol Journal subject: BIOLOGIA Year: 2012 Document type: Article Affiliation country: Brazil Country of publication: Brazil