Anatomy of corpus callosum in prenatally malnourished rats
Biol. Res
; 45(1): 87-92, 2012. ilus, tab
Article
in English
| LILACS
| ID: lil-626752
Responsible library:
CL1.1
ABSTRACT
The effect of prenatal malnutrition on the anatomy of the corpus callosum was assessed in adult rats (45-52 days old). In the prenatally malnourished animals we observed a significant reduction of the corpus callosum total area, partial areas, and perimeter, as compared with normal animals. In addition, the splenium of corpus callosum (posterior fifth) showed a significant decrease of fiber diameters in the myelinated fibers without changing density. There was also a significant decrease in diameter and a significant increase in density of unmyelinated fibers. Measurements of perimeter's fractal dimensions from sagittal sections of the brain and corpus callosum did not show significant differences between malnourished and control animals. These findings indicate that cortico-cortical connections are vulnerable to the prenatal malnutrition, and suggest this may affect interhemispheric conduction velocity, particulary in visual connections (splenium).
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Prenatal Exposure Delayed Effects
/
Corpus Callosum
/
Malnutrition
/
Nerve Fibers
Aspects:
Social determinants of health
Limits:
Animals
/
Pregnancy
Language:
English
Journal:
Biol. Res
Journal subject:
Biology
Year:
2012
Document type:
Article
/
Project document
Affiliation country:
Chile
/
Spain
Institution/Affiliation country:
Pontificia Universidad Católica de Chile/CL
/
Universidad Andrés Bello/CL
/
Universidad de Chile/CL
/
Universidad de Santiago/CL
/
Universidad de Zaragoza/ES