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Tratamiento de hepatitis C en la insuficiencia renal crónica terminal en hemodiálisis con Interferón 2 b y ribavirina: A case report / Presentación de 1 caso / Treatment of hepatitis C in end-stage chronic renal failure in hemodialysis with Interferon 2 b and ribavirine
Parodis López, Yanet; Pérez Rodríguez, Alexis; Arus Soler, Enrique; Gutiérrez, Francisco; Benítez Llanes, Orestes; Mármol Sóñora, Alexander.
Affiliation
  • Parodis López, Yanet; Instituto de Nefrología Dr. Abelardo Buch López. Ciudad de La Habana. CU
  • Pérez Rodríguez, Alexis; s.af
  • Arus Soler, Enrique; s.af
  • Gutiérrez, Francisco; s.af
  • Benítez Llanes, Orestes; s.af
  • Mármol Sóñora, Alexander; s.af
Rev. cuba. med ; 44(3/4)Mayo-ago. 2005.
Article in Spanish | LILACS | ID: lil-628837
Responsible library: CU1.1
RESUMEN
Se realizó la presentación clínica de un paciente de 32 años con antecedentes de salud hasta los 29 años de edad en que comienza a presentar una insuficiencia renal crónica terminal, se le aplicó tratamiento dialítico inmediatamente y 5 meses después se le diagnosticó una hepatitis C. Se decidió realizar trasplante renal donante vivo el cual no se puede efectuar dada la marcada citolisis existente, fue tratado inicialmente con interferón 2b durante un año sin negativizar el PCR por lo cual recibió posteriormente tratamiento combinado de interferón 2b y ribavirina (primer caso reportado en nuestro país en un paciente en hemodiálisis), se logró negativizar PCR, desapareció la citolisis y, finalmente, se logró el trasplante renal exitoso (donante vivo emparentado) 2 meses después de culminar el tratamiento. Se presentó la evolución bioquímica, hematológica y virológica con ambas terapéuticas.
ABSTRACT
The case of a 32-year-old male patient with past health until he was 29 years old, when he began to present an end-stage chronic renal failure, was reported. Dialytic treatment was immediately applied and 5 months later hepatitis C was diagnosed. It was decided to perform a kidney transplant from a living donor, but it was not possible due to the existence of a marked histolysis. He was initially treated with interferon 2b for a year without making the PCR negative. Therefore, he received combined treatment of interferon 2b and ribavirine (first case reported in our country of a patient undergoing hemodialysis). The PCR yielded negative, the cytolysis disappeared and the kidney transplant was successfully performed (from a living donor that was his relative) 2 months after concluding the treatment. The biochemical, hematological and virological evolution with both therapeutics was presented.

Full text: Available Collection: International databases Health context: SDG3 - Health and Well-Being Health problem: Target 3.3: End transmission of communicable diseases Database: LILACS Language: Spanish Journal: Rev. cuba. med Journal subject: Medicine Year: 2005 Document type: Article Affiliation country: Cuba Institution/Affiliation country: Instituto de Nefrología Dr. Abelardo Buch López/CU
Full text: Available Collection: International databases Health context: SDG3 - Health and Well-Being Health problem: Target 3.3: End transmission of communicable diseases Database: LILACS Language: Spanish Journal: Rev. cuba. med Journal subject: Medicine Year: 2005 Document type: Article Affiliation country: Cuba Institution/Affiliation country: Instituto de Nefrología Dr. Abelardo Buch López/CU
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