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Medición de nitratos y nitritos en agua y saliva de población rural precordillerana de la VIII región / Nitrate and nitrite in water and saliva of rural population in the Andes foothills of the VIII Region
Schmidt P, Thomas; Sedaghat N, Sahba; Rosel P, Pablo; Fierro T, Jorge.
Affiliation
  • Schmidt P, Thomas; Universidad de Concepción. CL
  • Sedaghat N, Sahba; Universidad de Concepción. CL
  • Rosel P, Pablo; Hospital Guillermo Grant Benavente. CL
  • Fierro T, Jorge; Hospital de Coronel. CL
Rev. otorrinolaringol. cir. cabeza cuello ; 72(2): 119-124, ago. 2012. tab
Article in Spanish | LILACS | ID: lil-651894
Responsible library: CL30.1
RESUMEN

Introducción:

Un factor de riesgo para las neoplasias escamosas de faringe son las nitrosaminas, las que derivan de los nitratos salivales que provienen de la dieta y en especial del agua si los niveles están por sobre la norma.

Objetivos:

Conocer y comparar los niveles de nitratos y nitritos en agua y saliva de habitantes de la región precordillerana y en población urbana de Concepción. Material y

método:

Estudio prospectivo, tipo caso y control. Determinan niveles de nitratos y nitritos en agua de la zona precordillerana y en agua de Concepción y en saliva de habitantes de la zona rural y de grupo control de Concepción.

Resultados:

Se obtienen 10 muestras de agua del sector rural y 1 muestra de agua potable de Concepción. Nivel de nitratos en agua rural 23,29 mg/L, en agua urbana 3,6 mg/L (p <0,05). En saliva, grupo estudio (n =15) con nivel de nitritos de 9,58 mg/ml, grupo control (n =24) nivel de 3,8 mg/ml (p <0,05).

Conclusión:

En la zona rural hay niveles significativamente mayores de nitratos en el agua y nitritos en saliva. Los niveles en agua son superiores a normas nacionales e internacionales. Nuestros resultados resaltan la posible importancia de las nitrosaminas y sus precursores como elementos carcinogónicos en los carcinomas escamosos orofaríngeos.
ABSTRACT

Introduction:

A risk factor for squamous carcinomas of the oropharynx are the nitrosamines, which are derived from salivary nitrate coming from diet and water, especially if the levels are above the allowed levels.

Aim:

To determine and compare the levels of nitrates and nitrites in drinking water and saliva of people at the foothills of our region and urban population of Concepcion. Material and

method:

A descriptive cross sectional study. Determination of levels of nitrates and nitrites in drinking water in the Andean foothills and Concepcion and in saliva of people from same locations.

Results:

We obtained 10 rural water samples and 1 from Concepcion drinking water. Nitrate levels in rural water were 23.29 mg/L and 3.6 mg/L (p <0.05) in urban water. In saliva, the study group (n =15) had 9.58 mg/ml nitrite in saliva, the control group (n =24) 3.8 mg/ml (p <0.05).

Conclusion:

In rural areas there are significantly higher levels of nitrates in drinking water and saliva. The water levels are higher than national and international standards. Our results confirm high amounts of nitrogen cycle products (nitrites and nitrates) in drinking water and in saliva so it could be considered as carcinogenic elements in oropharyngeal squamous cell carcinomas.
Subject(s)


Full text: Available Collection: International databases Database: LILACS Main subject: Carcinoma, Squamous Cell / Nitrates / Nitrites Type of study: Observational study / Risk factors Limits: Adolescent / Adult / Aged / Female / Humans / Male Country/Region as subject: South America / Chile Language: Spanish Journal: Rev. otorrinolaringol. cir. cabeza cuello Journal subject: Otolaryngology Year: 2012 Document type: Article Affiliation country: Chile Institution/Affiliation country: Hospital Guillermo Grant Benavente/CL / Hospital de Coronel/CL / Universidad de Concepción/CL

Full text: Available Collection: International databases Database: LILACS Main subject: Carcinoma, Squamous Cell / Nitrates / Nitrites Type of study: Observational study / Risk factors Limits: Adolescent / Adult / Aged / Female / Humans / Male Country/Region as subject: South America / Chile Language: Spanish Journal: Rev. otorrinolaringol. cir. cabeza cuello Journal subject: Otolaryngology Year: 2012 Document type: Article Affiliation country: Chile Institution/Affiliation country: Hospital Guillermo Grant Benavente/CL / Hospital de Coronel/CL / Universidad de Concepción/CL
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