Serologic survey of hantavirus in a rural population from the northern State of Mato Grosso, Brazil
Rev. Soc. Bras. Med. Trop
; 46(1): 30-33, Jan.-Feb. 2013. graf, tab
Article
in English
| LILACS
| ID: lil-666790
Responsible library:
BR1.1
ABSTRACT
INTRODUCTION:
Hantavirus is a genus of ribonucleic acid (RNA) viruses included in the family Bunyaviridae. Hantaviruses are rodent-borne zoonoses that, in the last 18 years, became an emergent public health problem in the Americas, causing a severe cardiopulmonary syndrome. This disease has no specific treatment and has a high case fatality. The transmission of hantavirus to man occurs by inhaling aerosols of rodent excreta. The aim of this study was to determine the prevalence of antibodies to hantavirus in the population of the rural settlement of Tupã in the county of Marcelândia, state of Mato Grosso, Brazil.METHODS:
The participants of the serologic survey were visited at their homes and selected randomly among the settlement population. Blood samples of the participants were collected by venopuncture. The serum samples were tested by an IgG-ELISA using an N recombinant protein of Araraquara hantavirus as antigen, using the protocol previously established by Figueiredo et al.RESULTS:
IgG antibodies to hantavirus were detected in 7 (13%) of the 54 participants. The positivity was higher among men. It was observed that there was an association of seropositivity to hantavirus within the participants born in the south of Brazil.CONCLUSIONS:
The results suggest that, in this rural area, everyone is exposed to the same risk of becoming infected with hantavirus, and, therefore, there is a need to intensify surveillance activities and education of the local people to prevent this viral infection.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Immunoglobulin G
/
Orthohantavirus
/
Hantavirus Infections
/
Antibodies, Viral
Type of study:
Diagnostic study
/
Practice guideline
/
Prevalence study
/
Risk factors
Limits:
Animals
/
Female
/
Humans
/
Male
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Rev. Soc. Bras. Med. Trop
Journal subject:
Tropical Medicine
Year:
2013
Document type:
Article
Affiliation country:
Brazil