Efficacy of HPA Lanolin® in treatment of lip alterations related to chemotherapy
J. appl. oral sci
; 21(2): 163-166, Mar-Apr/2013. graf
Article
in English
| LILACS
| ID: lil-674364
Responsible library:
BR1.1
ABSTRACT
The side effects of chemotherapy on the lips may cause esthetic and functional impact and increase the risk of infection. HPA Lanolin® is an option for supportive therapy because it has anti-inflammatory, antimicrobial and moisturizing properties. Objective:
To evaluate the efficacy of this product in the prevention of lip alterations in a population of patients undergoing chemotherapy. Material andMethods:
Patients undergoing chemotherapy (n = 57) were examined and distributed into two groups study (used HPA Lanolin®) and control (without supportive therapy on the lips). We evaluated the patients two weeks after chemotherapy, registering oral alterations, symptoms of pain, discomfort, limitation of mouth opening and dehydration, classified according to a visual analogue scale.Results:
Patients who used HPA Lanolin® had lower dehydration and experienced improvement of lip dryness (p<0.001). The main symptoms were dehydration, discomfort, limitation of mouth opening, pain. The main clinical signs were dry lips, mucositis, cheilitis, hematoma, swelling and cracking. We found no difference concerning the variables of pain, discomfort, and limitation of mouth opening between the study and control group.Conclusions:
We suggest that HPA Lanolin® is effective in reducing the symptoms of dehydration and the signs of lip dryness resulting from toxicity of chemotherapy, proving to be an interesting alternative supportive therapy for cancer patients.
Full text:
Available
Collection:
International databases
Health context:
Sustainable Health Agenda for the Americas
/
SDG3 - Health and Well-Being
Health problem:
Goal 9: Noncommunicable diseases and mental health
/
Target 3.4: Reduce premature mortality due to noncommunicable diseases
Database:
LILACS
Main subject:
Cosmetics
/
Lanolin
/
Lip
/
Antineoplastic Agents
Type of study:
Observational study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
J. appl. oral sci
Journal subject:
Dentistry
Year:
2013
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
University of São Paulo/BR