Correlación de los hallazgos endoscópicos e histológicos en el diagnóstico de metaplasia intestinal gástrica en pacientes referidos para endoscopia digestiva alta en la Clínica Colombia / Correlation of endoscopic and histological findings in diagnosis of gastrointestinal metaplasia in patients referred to the Clinica Colombia for upper endoscopies
Rev. colomb. gastroenterol
; 27(4): 263-268, oct.-dic. 2012. ilus
Article
in Es
| LILACS
| ID: lil-675264
Responsible library:
CO332
RESUMEN
Introducción:
La metaplasia intestinal es un paso más hacia el proceso final conocido del cáncer gástrico. Su correcta identificación endoscópica con toma de biopsia es vital para su confirmación histológica. No conocemos en nuestro medio la relación entre los hallazgos endoscópicos sospechosos de metaplasia intestinal y su confirmación histológica. El presento estudio busca determinar la verdadera correlación entre los hallazgos endoscópicos sugestivos de metaplasia y su contraparte histológica.Métodos:
Estudio observacional analítico, realizado en la Clínica Colombia donde se incluyeron pacientes con sospecha endoscópica de metaplasia intestinal, excluyendo pacientes con antecedente previo de metaplasia y con cáncer gástrico previo. La evaluación estadística se realizó con el software estadístico STATA 11.Resultados:
Se identificaron un total de 766 pacientes con sospecha endoscópica de metaplasia intestinal. En 543 de ellos se encontró confirmación histológica equivalente a un 70% del total de la muestra. Los hallazgos histológicos más frecuentes en el grupo en el que no se encontró correlación fueron gastritis crónica, gastropatía reactiva e hiperplasia foveolar entre otros. El valor predictivo positivo de los hallazgos endoscópicos fue cercano al 71%.Conclusiones:
Aunque la correlación fue cercana al 70%, se requieren de estudios prospectivos, multicéntricos y con cromoendoscopia, con el fin de evaluar la concordancia respectiva entre los dos métodos y determinar variables endoscópicas predictoras de severidad, y tipo de metaplasia para determinar protocolos de seguimiento para este tipo de pacientes.ABSTRACT
Introduction:
Intestinal metaplasia is one step towards the final process known as gastric cancer. Correct identification through a biopsy taken endoscopically is vital for histological confirmation. In our surroundings the relationship between endoscopic findings when intestinal metaplasia is suspected and histological confirmation are not understood. This study aims to determine the true correlation between endoscopic findings suggestive of metaplasia and their histological counterparts.Methods:
This was an observational and analytical study undertaken at the Clinica Colombia. Patients who were suspected of having intestinal metaplasia following endoscopic examinations were included. Patients with prior histories of metaplasia and gastric cancer were excluded. Statistical evaluation was performed using STATA 11.Results:
A total of 766 patients suspected of having intestinal metaplasias following endoscopic examination were included. 543 (70%) were confirmed histologically. Patients who most frequently had no correlation between suspicion following endoscopy and histological findings included those with chronic gastritis, foveolar hyperplasia, and reactive gastropathy. The positive predictive value of endoscopic findings was close to 71%.Conclusions:
Although the correlation was close to 70%, prospective and multicenter studies, as well as studies using chromoendoscopy, are needed in order to evaluate agreement between the two methods, to determine predictive endoscopic variables for severity and for types of metaplasia, and to determine protocols for monitoring these patients.Key words
Full text:
1
Collection:
01-internacional
Database:
LILACS
Main subject:
Statistics, Nonparametric
/
Endoscopy
/
Metaplasia
Type of study:
Clinical_trials
/
Diagnostic_studies
/
Evaluation_studies
/
Guideline
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Adult
/
Aged
/
Female
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Humans
/
Male
Country/Region as subject:
America do sul
/
Colombia
Language:
Es
Journal:
Rev. colomb. gastroenterol
Journal subject:
GASTROENTEROLOGIA
Year:
2012
Document type:
Article
Affiliation country:
Colombia
Country of publication:
Colombia