Diagnóstico incidental de hemocromatose hereditária pré-cirrótica / Incidental diagnosis of pre-cirrhotic hereditary hemochromatosis
GED gastroenterol. endosc. dig
; 30(4): 179-181, out.-dez. 2011. ilus
Article
in Portuguese
| LILACS
| ID: lil-678926
Responsible library:
BR9.1
RESUMO
O diagnóstico da hemocromatose hereditária (HH) em fase pré-cirrótica é um desafio, uma vez que os pacientes não apresentam sintomas ou sinais da doença. Relata-se caso de mulher de 62 anos que, submetida à colecistectomia videolaparoscópica para tratamento de coletilíase, apresentou fígado de aspecto alterado, sendo realizada biópsia hepática com agulha. O exame histológico do fígado pelo método de Perls mostrou grande quantidade de pigmento férrico, suspeitando-se de HH. Realizado estudo do metabolismo do ferro e teste genético para HH, confirmou-se a doença. A biópsia hepática, portanto, é de fundamental importância no diagnóstico da HH, devendo ser realizada toda vez que o cirurgião, por ocasião de cirurgia abdominal, observar fígado de aspecto não habitual.
ABSTRACT
The diagnosis of pre-cirrhotic hereditary hemochromatosis (HH) is difficult because there are no signs and symptoms in HH patients. We described a case of a 62-years old woman with cholelithiasis that was carried out a videolaparoscopic cholecystectomy. At surgery, the liver had been a altered aspect and liver needle biopsy was carried out. The histopathologic study by Persl method showed a great accumulation of iron pigment in hepatic tissue. The study of iron metabolism and genetic test for HH was released and the diagnosis of HH was confirmed. The liver biopsy is a gold standard procedure for diagnosis of HH and must be released when, at abdominal surgery, the surgeon to observe a liver with altered aspect.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Biopsy
/
Hemochromatosis
/
Liver
Type of study:
Diagnostic study
Limits:
Female
/
Humans
Language:
Portuguese
Journal:
GED gastroenterol. endosc. dig
Journal subject:
Gastroenterology
Year:
2011
Document type:
Article