Features to validate cerebral toxoplasmosis
Rev. Soc. Bras. Med. Trop
; Rev. Soc. Bras. Med. Trop;46(3): 373-376, May-Jun/2013. tab, graf
Article
in En
| LILACS
| ID: lil-679532
Responsible library:
BR1.1
ABSTRACT
Introduction Neurotoxoplasmosis (NT) sometimes manifests unusual characteristics. Methods We analyzed 85 patients with NT and AIDS according to clinical, cerebrospinal fluid, cranial magnetic resonance, and polymerase chain reaction (PCR) characteristics. Results In 8.5%, focal neurological deficits were absent and 16.4% had single cerebral lesions. Increased sensitivity of PCR for Toxoplasma gondii DNA in the central nervous system was associated with pleocytosis and presence of >4 encephalic lesions. Conclusions Patients with NT may present without focal neurological deficit and NT may occur with presence of a single cerebral lesion. Greater numbers of lesions and greater cellularity in cerebrospinal fluid improve the sensitivity of PCR to T gondii. .
Key words
Full text:
1
Collection:
01-internacional
Database:
LILACS
Main subject:
Toxoplasmosis, Cerebral
/
AIDS-Related Opportunistic Infections
Type of study:
Diagnostic_studies
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
En
Journal:
Rev. Soc. Bras. Med. Trop
Journal subject:
MEDICINA TROPICAL
Year:
2013
Document type:
Article
Affiliation country:
Brazil
Country of publication:
Brazil