Essential thrombocythemia: a rare disease in childhood
Rev. bras. hematol. hemoter
; Rev. bras. hematol. hemoter;35(4): 287-289, 2013. tab
Article
in En
| LILACS
| ID: lil-687926
Responsible library:
BR408.1
ABSTRACT
Essential thrombocythemia is an acquired myeloproliferative disorder characterized by the proliferation of megakaryocytes in bone marrow, leading to a persistent increase in the number of circulating platelets and thus increasing the risk for thrombotic and hemorrhagic events. The disease features leukocytosis, splenomegaly, vascular occlusive events, hemorrhages and vasomotor disorders. The intricate mechanisms underlying the molecular pathogenesis of this disorder are not completely understood and are still a matter of discussion. Essential thrombocythemia is an extremely rare disorder during childhood. We report on a case of essential thrombocythemia in a child and discuss the diagnostic approach and treatment strategy.
Key words
Full text:
1
Collection:
01-internacional
Database:
LILACS
Main subject:
Blood Banks
/
Blood Donors
/
Temporal Distribution
Limits:
Humans
Language:
En
Journal:
Rev. bras. hematol. hemoter
Journal subject:
HEMATOLOGIA
Year:
2013
Document type:
Article
Affiliation country:
Brazil
Country of publication:
Brazil