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Aureobasidium pullulans infection in a patient with chronic lymphocytic leukemia
Oliveira, Leonardo Rodrigues de; Moraes-Souza, Helio; Maltos, Andre Luiz; Santos, Keila Cristina dos; Molina, Rodrigo Juliano; Barata, Cristina Hueb.
Affiliation
  • Oliveira, Leonardo Rodrigues de; Universidade Federal do Triangulo Mineiro. Servico de Hematologia. Uberaba. BR
  • Moraes-Souza, Helio; Universidade Federal do Triangulo Mineiro. Servico de Hematologia. Uberaba. BR
  • Maltos, Andre Luiz; Universidade Federal do Triangulo Mineiro. Servico de Hematologia. Uberaba. BR
  • Santos, Keila Cristina dos; Universidade Federal do Triangulo Mineiro. Servico de Hematologia. Uberaba. BR
  • Molina, Rodrigo Juliano; Universidade Federal do Triangulo Mineiro. Servico de Hematologia. Uberaba. BR
  • Barata, Cristina Hueb; Universidade Federal do Triangulo Mineiro. Servico de Hematologia. Uberaba. BR
Rev. Soc. Bras. Med. Trop ; 46(5): 660-662, Sept-Oct/2013. graf
Article in English | LILACS | ID: lil-691412
Responsible library: BR1.1
ABSTRACT
Saprophytic fungi are being increasingly recognized as etiologic agents of mycoses in immunosuppressed patients. We report a case of subcutaneous infiltration by Aureobasidium pullulans, likely due to traumatic inoculation, in a neutropenic patient during chemotherapy for chronic lymphocytic leukemia. The patient was treated with amphotericin B deoxycholate but was subsequently switched to itraconazole, which improved the lesion. This case highlights the importance of considering unusual fungal infections in critically ill patients such as those who are immunosuppressed due to chemotherapy. Diagnostic techniques and effective antifungal therapy have improved the prognosis of these cases.
Subject(s)

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Full text: Available Collection: International databases Database: LILACS Main subject: Ascomycota / Leukemia, Lymphocytic, Chronic, B-Cell / Febrile Neutropenia / Mycoses Type of study: Prognostic study Limits: Aged / Humans / Male Language: English Journal: Rev. Soc. Bras. Med. Trop Journal subject: Tropical Medicine Year: 2013 Document type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal do Triangulo Mineiro/BR
Fulltext
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Full text: Available Collection: International databases Database: LILACS Main subject: Ascomycota / Leukemia, Lymphocytic, Chronic, B-Cell / Febrile Neutropenia / Mycoses Type of study: Prognostic study Limits: Aged / Humans / Male Language: English Journal: Rev. Soc. Bras. Med. Trop Journal subject: Tropical Medicine Year: 2013 Document type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal do Triangulo Mineiro/BR