Phytochemical Profile and Qualification of Biological Activity of an Isolated Fraction of Bellis perennis
Biol. Res
; 46(3): 231-238, 2013. ilus, graf, tab
Article
in English
| LILACS
| ID: lil-692188
Responsible library:
CL1.1
ABSTRACT
This study describes the isolation and identification of apigenin-7-O-ghicopyranoside, a flavonoid isolated from the flowers of Bellis perennis L., Asteraceae, an species with a broad spectrum of biological activities. The in vitro antioxidant activity and the inhibition of the enzyme acetylcholinesterase were evaluated. The flavonoid showed strong in vitro antioxidant potential, because of the capacity of removal of hydroxyl radicals and nitric oxide, and also prevented the formation of thiobarbituric acid-reactive substances. These parameters were inhibited at the highest concentration of ApG at rates of 77.7%, 72% and 73.4%, respectively, in addition to inhibiting acetylcholinesterase, suggesting potential use in the treatment of neurodegenerative diseases.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Plant Extracts
/
Cholinesterase Inhibitors
/
Asteraceae
/
Flowers
/
Antioxidants
Language:
English
Journal:
Biol. Res
Journal subject:
Biology
Year:
2013
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Federal University of Piauí/BR