Neutrophil-to-lymphocyte ratio and in-hospital mortality in patients with acute heart failure
Clinics
; 69(3): 190-193, 3/2014. tab, graf
Article
in English
| LILACS
| ID: lil-703606
Responsible library:
BR1.1
ABSTRACT
OBJECTIVES:
Previous studies have demonstrated the role of inflammation in acute heart failure. The neutrophil-to-lymphocyte ratio was found to be a useful inflammatory marker for predicting adverse outcomes. We hypothesized that an elevated neutrophil-to-lymphocyte ratio would be associated with increased mortality in acute heart failure patients.METHODS:
The study cohort consisted of 167 acute heart failure patients with an ejection fraction <50%. The primary endpoint was in-hospital mortality, and the patients were divided into two groups according to in-hospital mortality.RESULTS:
In a multivariate regression analysis, including baseline demographic, clinical, and biochemical covariates, the neutrophil to lymphocyte ratio remained an independent predictor of mortality (OR 1.156, 95% CI 1.001 - 1.334, p = 0.048).CONCLUSION:
In conclusion, an elevated neutrophil-to-lymphocyte ratio seems to be a predictor of short-term mortality in patients with acute heart failure and a reduced left ventricular ejection fraction. .
Full text:
Available
Collection:
International databases
Health context:
SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases
Health problem:
Cardiovascular Disease
/
Other Blood Disorders
/
Other circulatory Diseases
Database:
LILACS
Main subject:
Lymphocytes
/
Hospital Mortality
/
Heart Failure
/
Neutrophils
Type of study:
Diagnostic study
/
Etiology study
/
Incidence study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Aged
/
Aged, 80 and over
/
Female
/
Humans
/
Male
Language:
English
Journal:
Clinics
Journal subject:
Medicine
Year:
2014
Document type:
Article
Affiliation country:
Turkey
Institution/Affiliation country:
Bezmialem University/TR