The effect of fluoride toothpaste on root dentine demineralization progression: a pilot study
Braz. oral res
; 28(spe): 1-5, 14/01/2014. graf
Article
in English
| LILACS
| ID: lil-704641
Responsible library:
BR1.1
ABSTRACT
The anticaries effect of fluoride (F) toothpaste containing 1100 µg F/g in reducing enamel demineralization is well established, but its effect on dentine has not been extensively studied. Furthermore, it has been shown that toothpaste containing a high F concentration is necessary to remineralize root dentine lesions, suggesting that a 1100 µg F/g concentration might not be high enough to reduce root dentine demineralization, particularly when dentine is subjected to a high cariogenic challenge. Thus, the aim of this pilot study was to evaluate in situ the effect of F toothpaste, at a concentration of 1100 µg F/g, on dentine demineralization. In a crossover and double-blind study, conducted in two phases of 14 days, six volunteers wore a palatal appliance containing four slabs of bovine root dentine whose surface hardness (SH) was previously determined and to which a 10% sucrose solution was applied extra-orally 8×/day. Volunteers used a non-F toothpaste (negative control) or F toothpaste (1100 µg F/g, NaF/SiO2) three times a day. On the 10th and 14th days of each phase, two slabs were collected and SH was determined again. Dentine demineralization was assessed as percentage of SH loss (%SHL). The effect of toothpaste was significant, showing lower %SHL for the F toothpaste group (42.0 ± 9.7) compared to the non-F group (62.0 ± 6.4; p < 0.0001), but the effect of time was not significant (p > 0.05). This pilot study suggests that F toothpaste at 1100 µg F/g is able to decrease dentine caries even under a high cariogenic challenge of biofilm accumulation and sugar exposure.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Toothpastes
/
Cariostatic Agents
/
Tooth Demineralization
/
Fluorides
Type of study:
Controlled clinical trial
/
Observational study
Limits:
Animals
/
Humans
Language:
English
Journal:
Braz. oral res
Journal subject:
Dentistry
Year:
2014
Document type:
Article
/
Project document
Affiliation country:
Brazil
Institution/Affiliation country:
University of Campinas/BR