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Morphological patterns and malignancy criteria of transmissible venereal tumor in cytopathological and histopathological exams / Padrões morfológicos e critérios de malignidade do tumor venéreo transmissível aos exames citopatológico e histopatológico
Lima, Caroline Rocha de Oliveira; Rabelo, Rogério Elias; Vulcani, Valcinir Aloisio Scalla; Furtado, Adriana Pereira; Helrigel, Panmera Almeida; Brito, Luiz Augusto Batista; Moura, Veridiana Maria Brianezi Dignani de.
Affiliation
  • Lima, Caroline Rocha de Oliveira; Federal University de Goias. School of Veterinary Medicine and Animal Science. Jataí. BR
  • Rabelo, Rogério Elias; UFG. Department of Veterinary Medicine. Jataí. BR
  • Vulcani, Valcinir Aloisio Scalla; UFG. Department of Veterinary Medicine. Jataí. BR
  • Furtado, Adriana Pereira; UFG. EVZ. Goiânia. BR
  • Helrigel, Panmera Almeida; UFG. Veterinary Medicine. Jataí. BR
  • Brito, Luiz Augusto Batista; UFG. Department of Veterinary Medicine, Animal Pathology. Goiânia. BR
  • Moura, Veridiana Maria Brianezi Dignani de; UFG. Department of Veterinary Medicine, Animal Pathology. Goiânia. BR
Braz. j. vet. res. anim. sci ; 50(3): 238-246, 2013. tab, ilus
Article in En | LILACS | ID: lil-707770
Responsible library: BR68.1
ABSTRACT
The aim of this study was to identify morphological patterns and malignancy criteria of the TVT in cytopathological and histopathological evaluations and relate these characteristics to clinical evolution and response to chemotherapy. Regarding studied animals, sixteen dogs were female and four were male. The age of the animals ranged between one and ten years old. Considering breed, 80% of the dogs were mongrel dogs and 20% were of other breeds. It was found that the cytological samples allowed a better characterization of the cell type than histological ones. The plasmacytoid was the most common morphological type of TVT, followed by the lymphocytoid and mixed standards. There was no difference among the scores for the malignancy criteria and morphological types of TVT. Regarding response to chemotherapy, no morphological type of the TVT showed any difference, but the TVT presents morphological peculiarities that may interfere with tumor behavior, especially those related to increased aggressiveness and that are observed in the plasmacytoid TVT.
RESUMO
Este estudo teve por objetivo identificar os padrões morfológicos e os critérios de malignidade do TVT aos exames citológico e histopatológico e relacionar essas características à evolução clínica e à resposta à quimioterapia. Dos ani- mais estudados, dezesseis cães eram fêmeas e quatro machos. A idade dos animais variou entre um e dez anos de idade. Quanto à raça, 80% dos cães eram sem raça definida e 20% de outras raças. Constatou-se que as amostras citológicas permitiram melhor caracterização do tipo celular do que as histológicas. O TVT tipo plasmocitoide foi o de maior ocor- rência, seguido pelos padrões linfocitoide e misto. Não houve diferença entre os escores estabelecidos para os critérios de malignidade e os tipos do TVT. Nenhum tipo morfológico do TVT diferiu quanto à resposta quimioterápica, mas o TVT apresenta particularidades morfológicas que podem interferir no comportamento tumoral, especialmente aquelas relacionadas à maior agressividade, e que são observadas no TVT plasmocitoide.
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Full text: 1 Collection: 01-internacional Database: LILACS Main subject: Drug Therapy / Neoplasms Type of study: Guideline / Prognostic_studies Limits: Animals Language: En Journal: Braz. j. vet. res. anim. sci Journal subject: MEDICINA VETERINARIA Year: 2013 Document type: Article Affiliation country: Brazil Country of publication: Brazil
Full text: 1 Collection: 01-internacional Database: LILACS Main subject: Drug Therapy / Neoplasms Type of study: Guideline / Prognostic_studies Limits: Animals Language: En Journal: Braz. j. vet. res. anim. sci Journal subject: MEDICINA VETERINARIA Year: 2013 Document type: Article Affiliation country: Brazil Country of publication: Brazil