Concordancia de la citología por punción con aguja fina para la detección de cáncer de tiroides en pediatría / Diagnostic yield of fine-needle aspiration cytology for the detection of thyroid cancer in pediatric patients
Rev. méd. Chile
; 142(3): 330-335, mar. 2014. tab
Article
in Spanish
| LILACS
| ID: lil-714357
Responsible library:
CL1.1
ABSTRACT
Background:
Despite the low frequency of thyroid nodules (TN) in children, one of every four is malignant. Fine-needle aspiration cytology (FNAC) has a high accuracy detecting thyroid cancer.Aim:
To evaluate the performance of FNAC in TN in Chilean children to detect thyroid cancer. Patients andMethods:
The pathological reports of 77 thyroidectomies and 103 FNAC carried out in patients aged less than 18 years, between 2002 and 2013 were reviewed. In 36 patients aged 15 ± 2 years (77% women), both the reports of the thyroidectomy and FNAC were available. The cytological specimens were reclassified based on Bethesda 2010. The histology was classified as benign (nodular hyperplasia and follicular adenoma, n = 18), or malignant (papillary, follicular and medullar carcinoma, n = 18). The concordance of the cytology with the final biopsy report was calculated.Results:
FNAC classified 13 specimens as definitively benign and 13 as definitively malignant. Among these, these concordances with the pathological study of the biopsy was 100%. Of six cytology tests considered "suspicious for follicular neoplasm" by FNAC, four were benign (67%), and two malignant (33%). Of four cytology tests considered "suggestive of carcinoma" by FNAC, one was benign (25%), and three malignant (75%).Conclusions:
Among the studied children, there was a good concordance between FNAC and surgical biopsies. Therefore a FNAC should be carried out when malignancy is suspected in pediatric patients with a TN.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Thyroid Gland
/
Thyroid Neoplasms
Type of study:
Diagnostic study
/
Observational study
/
Risk factors
Limits:
Adolescent
/
Child
/
Female
/
Humans
/
Male
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2014
Document type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Pontificia Universidad Católica de Chile/CL