Accuracy of oral exfoliative cytology in Sudanese patients undergoing oral biopsy
RSBO (Impr.)
; 8(3): 255-260, Jul.-Sep. 2011. tab
Article
in English
| LILACS
| ID: lil-720310
Responsible library:
BR97.1
ABSTRACT
Introduction:
Early detection of a premalignant or malignant oral lesions promises to improve the survival and the morbidity of patients suffering from these conditions. Oral exfoliative cytology (OEC) is a non-invasive method that is well accepted by the patient, and is therefore, suitable for screening at-risk population for early diagnosis of oral cancer.Objective:
The purpose of this study is to investigate the value of OEC in the detection of oral premalignant and malignant lesions. Material andmethods:
In this hospital-based case-control study, cytological scrapes from buccal mucosa were obtained from 100 individuals, of whom 50 were patients with oral lesions ascertained as "cases" and 50 were clinically healthy volunteers ascertained as "controls". All patients with oral lesions were also subjected to oral biopsy and histological examination.Results:
Out of 50 cases studied, histopathology showed the presence of Oral squamous cell carcinoma OSCC (n = 28), leukoplakia (n = 8), dysplasia (n = 3), and benign normal lesions (n = 11). In cytology, a specificity of 100%, sensitivity of 93% and accuracy of 92% were obtained for OSCC. Leukoplakia gave a specificity of 100%, a sensitivity of 87.5%, and an accuracy of 95%.Conclusion:
Despite the small number of cases in this study, OEC is a useful method for detecting oral premalignant and malignant lesions. OEC can detect a number of pathological conditions that require management.
Full text:
Available
Collection:
International databases
Database:
LILACS
Type of study:
Observational study
/
Risk factors
/
Screening study
Language:
English
Journal:
RSBO (Impr.)
Journal subject:
Dentistry
Year:
2011
Document type:
Article