Prevalencia y perfil de sensibilización a aeroalérgenos en 1.199 niños asmáticos: serie consecutiva de casos / Prevalence of atopy in 1,199 asthmatic children from southern Santiago, Chile
Rev. méd. Chile
; 142(5): 567-573, mayo 2014. ilus
Article
in Spanish
| LILACS
| ID: lil-720664
Responsible library:
CL1.1
ABSTRACT
Background:
The prevalence of atopy in asthmatic children is widely variable around the world as demonstrated by large multicentric international studies.Aim:
To determine the prevalence of atopy, defined as a positive reaction to one or more allergens in the skin prick test (SPT), in children with persistent asthma. Material andMethods:
We studied 1,199 children (54% male), aged between 4 and 16 years with confirmed diagnosis of asthma and followed at a Department of Pediatric Respiratory Medicine, between 2006 and 2011. SPT was performed according to international recommendations using standardized aeroallergens, in the forearm. A positive reaction was defined as a wheal ≥ 3 mm to one or more allergens.Results:
The overall prevalence of atopy (positive SPT) was 49.4% (95% confidence interval (CI) 46.5-52.2) and there was a significant trend towards a higher prevalence with increasing age (p < 0.01). The main allergens with positive reactions were Dermatophagoides with 24.9% (95% CI 26.7-31.9), grass 24.0% (95% CI 21.6-26.5), weeds 19.0% (95% CI 16.9-21.4), cat 17.7% (95% CI 15.4-20.2), and Alternaria with 11.0% (95% CI 9.1-13.1). Sixty five percent of positive children reacted to one or more allergens. There were no adverse reactions.Conclusions:
In the southern metropolitan area of Santiago de Chile, half of children with asthma are sensitized to common aeroallergens.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Asthma
/
Allergens
/
Hypersensitivity
Type of study:
Controlled clinical trial
/
Etiology study
/
Practice guideline
/
Prevalence study
/
Risk factors
/
Screening study
Limits:
Animals
/
Female
/
Humans
/
Male
Country/Region as subject:
South America
/
Chile
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2014
Document type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Hospital CRS El Pino/CL